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The Polycomb group (PcG) and Trithorax group (TrxG) proteins are key epigenetic regulators controlling silenced and active states of genes in multicellular organisms, respectively. In Drosophila PcG/TrxG proteins are recruited to chromatin via binding to specialized DNA-elements termed Polycomb Resp...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-05-22 | PXD029459 | Pride
Transcription factors are one of the major groups of proteins whose suppression leads to tumor growth arrest. Different types of cancer express a specific set of transcription factors that establish and maintain specific gene expression patterns. In prostate cancer cells, one of the key transcriptio...
ORGANISM(S): Homo sapiens (Human) 
2025-11-06 | PXD059115 | Pride
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