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ProteomicsLabel-free quantitative proteomics reveals synergistic mechanism of a new erythromycin derivative and oxacillin against methcillin-resistant S. aureus
Methicillin-resistant Staphylococcus aureus (MRSA) remains a global health threat with an over 14% fatality rate, in case of invasive infection, in 2011. Multi-drug resistance is the main reason for the failure of therapy. Use of antimicrobial drug combinations with synergistic effect is increasingl...
ORGANISM(S): Staphylococcus aureus 
2022-03-01 | PXD001494 | Pride
Key words: synergistic effect Label-free quantitative proteomics Oxacillin， methicillin-resistant s. aureus Erythromycin derivative 
UnknownProteomic response of methicillin-resistant S. aureus to a synergistic antibacterial drug combination: a novel erythromycin derivative and oxacillin.
Not available
S-EPMC4726183 | biostudies-literature
UnknownEthyl-substituted erythromycin derivatives produced by directed metabolic engineering.
Not available
S-EPMC22598 | biostudies-literature
UnknownSPR741, Double- or Triple-Combined With Erythromycin and Clarithromycin, Combats Drug-Resistant Klebsiella pneumoniae, Its Biofilms, and Persister Cells.
Not available
S-EPMC8971605 | biostudies-literature
UnknownA novel macrolide derivative ameliorates smoke-induced inflammation and emphysema by inhibiting NF-κB activation.
Not available
S-EPMC8014339 | biostudies-literature
ProteomicsProteome-wide adaptation of Lactococcus cremoris under temperature changes or translation inhibition
Growth conditions influence growth rate and the corresponding global proteome composition. It is commonly observed that a higher ribosomal content due to growth rate optimization may impact the level of metabolic proteins. In the case of Lactococcus cremoris, acidification and flavor formation are i...
ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363 
2025-02-17 | PXD042113 | Pride
Temperature Proteome allocation Lactococcus cremoris Protein coexpression Translation inhibitor 
UnknownAnti-ultraviolet, antibacterial, and biofilm eradication activities against Cutibacterium acnes of melanins and melanin derivatives from Daedaleopsis tricolor and Fomes fomentarius.
Not available
S-EPMC10803019 | biostudies-literature
UnknownSynthesis of new 1,4-dihydropyridine derivative, anti-cancer, bacterial activity, molecular docking and adsorption, distribution, metabolism and excretion analysis.
Not available
S-EPMC11622802 | biostudies-literature
UnknownDifferences in the Propensity of Different Antimicrobial Resistance Determinants to Be Disseminated via Transformation in Campylobacter jejuni and Campylobacter coli.
Not available
S-EPMC9227638 | biostudies-literature
UnknownDesmethyl Macrolide Analogues to Address Antibiotic Resistance: Total Synthesis and Biological Evaluation of 4,8,10-Tridesmethyl Telithromycin.
Not available
S-EPMC3105755 | biostudies-literature
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