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TranscriptomicsEffect of erythropoietin on cerebral ischemia-induced changes in gene expression in rats
Analysis of the gene expression profile in the cerebral cortex of rats 2h or 6h after middle cerebral artery occlusion with or without a single erythropoietin treatment 6 conditions with each 3 replicates, hybridized with 1 color.
ORGANISM(S): Rattus norvegicus 
2012-05-31 | E-GEOD-33725 | biostudies-arrayexpress
TranscriptomicsErythropoietin use in kidney transplants
Background and objectives: This report describes an unusual presentation of severe hypertension (HTN) in a subset of pediatric kidney recipients treated with a steroid avoidance pediatric renal transplantation protocol. The HTN was secondary to atypical, reno-vascular abnormalities (RVA) of the tran...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-13198 | biostudies-arrayexpress
TranscriptomicsExpression profiles of bone marrow cells from model mice for erythropoietin-deficiency anemia (ISAM)
We established a novel mouse model for postnatal erythropoietin (Epo)-deficiency anaemia, designated ISAM (inherited super anemic mouse), using a transgenic complementation rescue technique. To identify Epo-regulated genes in vivo, we examined the mRNA expression profile in the bone marrow of ISAM 6...
ORGANISM(S): Mus musculus 
2013-01-18 | E-GEOD-43585 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of human whole-blood samples before and after the administration of recombinant human erythropoietin
As part of cross-platform comparisons of microarray and RNA-seq, this current experiment using the Affymetrix Human Transcriptome Array 2.0 aimed to quantify gene-level expression in subjects administered recombinant human erythropoietin over a 10-week protocol for the identification of gene signatu...
ORGANISM(S): Homo sapiens 
2021-11-04 | E-MTAB-11080 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human stable end-stage renal disease patients reveals nocturnal hemodialysis improves erythropoietin responsiveness
Nocturnal home hemodialysis (NHD) [5 – 6 times a week, 6-8 hours per session] augments uremia clearance and is associated with an increase in hemoglobin level. We have used microarray to have a global image of the changes at the gene expression. Experiment Overall Design: Sixteen stable end-sta...
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-11227 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of high-dose recombinant erythropoietin treatment of unilateral brain injury in neonatal mouse hippocampus
Comparison of gene expression in the hippocampus of 10 day old sham-injured and brain-injured BALB-c mice, and examine the effects of high dose Epo on these conditions at 24 hours following injury. Four groups of six mice were treated with epo/no epo, injured/not injured.
ORGANISM(S): Mus musculus 
2015-12-11 | E-GEOD-75865 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles of kidneys that underwent reversible UUO model using model mice for erythropoietin-deficiency anemia (ISAM)
We have established a novel mouse model for postnatal erythropoietin (Epo)-deficiency anaemia, designated ISAM (inherited super anemic mouse) using a transgenic complementation rescue technique. To identify responsible signals for myofibroblastic transformation of Renal Erythropoietin-producing cell...
ORGANISM(S): Mus musculus 
2013-03-20 | E-GEOD-45304 | biostudies-arrayexpress
ProteomicsProteome of Erythropoietin-induced mouse CFU-E cells
Time-resolved CFU-E proteome was analyzed by time collapsed super-SILAC with erythropoietin-stimulated BaF3-mEpoR proteome as internal heavy standard.
ORGANISM(S): Mus musculus (Mouse) 
2022-09-28 | PXD004539 | Pride
Cfu-e Mouse Epo Tcsuper-silac 
TranscriptomicsEffect of erythropoietin on primed leukocyte expression profile
Resistance to erythropoietin (EPO) treatment is observed in a considerable proportion of anemic patients with chronic kidney disease. Previous reports suggest that inflammation is one of the major independent predictors of this resistance, and pro-inflammatory cytokines have been shown to inhibit er...
ORGANISM(S): Homo sapiens 
2013-12-19 | E-GEOD-53336 | biostudies-arrayexpress
TranscriptomicsErythropoietin promotes breast tumorigenesis through tumor initiating cell self-renewal
The erythropoietin (EPO) hormone induces red blood cell production and its recombinant form is the most prescribed drug for the treatment of anemia, including that arising in cancer patients. Based on randomized trials showing that EPO administration to cancer patients result in a decreased survival...
ORGANISM(S): Homo sapiens 
2014-05-31 | E-GEOD-51433 | biostudies-arrayexpress
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