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TranscriptomicsEffect of erythropoietin (EPO) and leukemia-inhibitory factor (LIF) on gene expression profiling in differentiating rat CG4-EPOR oligodendrocytes
Analysis of the gene expression profile in differentiating rat CG4-EPOR oligodendrocytes treated with EPO, LIF or their combination for 1h or 20h Gene expression was measured undifferentiated CG4-EPOR cells and in differentiating cells at 1h and 20h in 5 conditions: control, EPO 10ng/ml, LIF 0.2ng/m...
ORGANISM(S): Rattus norvegicus 
2016-07-22 | E-GEOD-84687 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human erythroid progenitors cultured with or without EPO in combination with LY294002
CD34+ progentitors were isolated from the bone marrow of three healthy volunteers. CD34+CD71+CD45RA- were FACS sorted to enrich for erythroid progenitors. The cells were cultured for four hours with or without EPO in combination with LY294002, and harvested for RNA extraction, amplification and expr...
ORGANISM(S): Homo sapiens 
2006-11-10 | E-SMDB-3500 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD34+ treated with EPO at day 7 and 14 to investigate the effect of EPO on erythroid maturation.
To study transcriptional profiles in human CD34+ cell in EPO condition on day 7 and day 14. Experiment Overall Design: After obtaining informed consent, human CD34+ cells were isolated in high purity from the peripheral blood of normal human volunteers. The cells were cultured at a concentration of ...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7874 | biostudies-arrayexpress
ProteomicsSupporting information for tryptic EPO glycopeptide LC-MS analysis via cysteine aminoethylation
Supplementary information for a technical note describing the application of cysteine aminoethylation for the site-specific glycosylation analysis of recombinant human EPO using trypsin as sole protease.
ORGANISM(S): Cho Cells 
2020-04-21 | MSV000085318 | MassIVE
GenomicsEpo producing cell lines
Generation of mouse renal Epo-producing (REP) cell lines by conditional gene tagging
PRJEB19328 | ENA
TranscriptomicsErythropoietin use in kidney transplants
Background and objectives: This report describes an unusual presentation of severe hypertension (HTN) in a subset of pediatric kidney recipients treated with a steroid avoidance pediatric renal transplantation protocol. The HTN was secondary to atypical, reno-vascular abnormalities (RVA) of the tran...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-13198 | biostudies-arrayexpress
ProteomicsProteome of BaF3-mEpoR cells stimulated with 5 U/ml Epo, 10 ng/ml IL-3 or left untreated
The proteome of BaF3-mEpoR cells stimulated with 5 U/ml Epo, 10 ng/ml IL-3 or left untreated were analyzed by label free LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2022-09-28 | PXD035181 | Pride
Baf3 Interleukin-3 Mouse Erythropoietin 
GenomicsReceptor-mediated mitophagy regulates EPO production and protects against renal anemia
Receptor-mediated mitophagy regulates EPO production and protects against renal anemia
PRJNA664995 | ENA
TranscriptomicsTranscription profiling of mouse treated with erythropoietin(EPO) and vehicle (VEH) after hypoxic-ischemic (HI) injury to gain insight into the mechanisms underlying the neuroprotective effects of EPO
Hypoxic-ischemic (HI) injury in the developing brain is a common cause of disability in children, and there are no effective treatments at this time. Erythropoietin (EPO) has recently gained interest as a neuroprotective drug, and EPO and its receptor are expressed within the central nervous system....
ORGANISM(S): Mus musculus 
2007-11-06 | E-GEOD-1999 | biostudies-arrayexpress
GenomicsEpo-Induced Erythroid Maturation Is Dependent on Plcγ1 Signaling
Erythropoiesis is a tightly regulated process. Development of red blood cells occurs through differentiation of hematopoietic stem cells into more committed progenitors and finally into erythrocytes. Binding of erythropoietin to its receptor (EpoR) is strictly required for erythropoiesis as it promo...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-60087 | biostudies-arrayexpress
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