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MetabolomicsMetabolomics of human primary B-ALL cells treated by BCR-Abl1 inhibitor, STI571, and p190 BCR-Abl+ BAF3 cells with ASS1 knockdown
Analyze the Metabolomics changes in B-ALL cells after the treatment of imatinib and p190+ BAF3 cells with ASS1 knockdown or left untreated. two methods as the below LC-MS description showed were used.
2026-07-08 | MTBLS14638 | MetaboLights
TranscriptomicsJAK2 Naive and Persitent Murine BaF3 cells infected with MPLW515L
Transcriptional profiling of Murine BaF3 cells infected with MPLW515L grown under either normal conditions (Naive) or in 0.8 uM INCB18424 for 4-6 weeks (Persistent). Naive and Persistent cells were then treated with either DMSO (Control) or 0.8 uM INCB18424 for 4 hours. Goal was to determine transcr...
ORGANISM(S): Mus musculus 
2012-05-30 | E-GEOD-38335 | biostudies-arrayexpress
ProteomicsProteome of BaF3-mEpoR cells stimulated with 5 U/ml Epo, 10 ng/ml IL-3 or left untreated
The proteome of BaF3-mEpoR cells stimulated with 5 U/ml Epo, 10 ng/ml IL-3 or left untreated were analyzed by label free LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2022-09-28 | PXD035181 | Pride
Baf3 Interleukin-3 Mouse Erythropoietin 
TranscriptomicsAnalysis of mouse T cell transcription profile after co-culture with BaF3 cells with or without the oncogenic point mutation JAK2 V617F
The activation of PD-1 (Programmed Death receptor-1) on T cells can cause T cell exhaustion and immune tolerance. Some tumors up-regulate the expression of the ligand of PD-1, namely PD-L1 (Programmed Death Receptor-Ligand 1), thus preventing anti-tumor immune response and promoting immune-escape. P...
ORGANISM(S): Mus musculus 
2018-12-01 | E-MTAB-5028 | biostudies-arrayexpress
GenomicsGene expression profile of Baf3 cells overexpressing TPR-FGFR1 fusion gene
Gene expression profile of Baf3 cells overexpressing TPR-FGFR1 fusion gene
PRJNA1137402 | ENA
GenomicsmRNA expression quantitative Analysis of BaF3-T315I cell lines treated with I13 compared with control
mRNA expression quantitative Analysis of BaF3-T315I cell lines treated with I13 compared with control
PRJNA937603 | ENA
TranscriptomicsJAK2 Naive and Persitent Murine BaF3 cells infected with MPLW515L
Transcriptional profiling of Murine BaF3 cells infected with MPLW515L grown under either normal conditions (Naive) or in 0.8 uM INCB18424 for 4-6 weeks (Persistent). Naive and Persistent cells were then treated with either DMSO (Control) or 0.8 uM INCB18424 for 4 hours. Goal was to determine transcr...
ORGANISM(S): Mus musculus 
2012-05-31 | GSE38335 | GEO
Genomicsthe mRNA expression quantitative Analysis of K562 and BaF3-T315I treated with JOA compared with control.
the mRNA expression quantitative Analysis of K562 and BaF3-T315I treated with JOA compared with control.
PRJNA863114 | ENA
GenomicsRNA-seq of NOTCH1 mutation in chronic lymphocytic leukemia cell BaF3.
RNA-seq of NOTCH1 mutation in chronic lymphocytic leukemia cell BaF3.
PRJNA475876 | ENA
TranscriptomicsGene expression profile of Baf3 cells conditionally expressing BCR-ABL in presence and absence of Growth factor IL-3
The Baf3 are dependent on IL-3 for grwoth however transformation by BCR -ABL oncogene causes BAf3 cells independent of IL-3. The BAf3 cells expressing BCR-ABL are dependent on continuous expression of BCR_ABL for growth. Inhibitionof BCR-ABL by its inhibitor Imatinib cause these cells to undergo apo...
ORGANISM(S): Mus musculus 
2017-03-20 | GSE75057 | GEO
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