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Epitope mapping of the protein ESAT6 and nanobody rvES6 using HDX-MS.
ORGANISM(S): Homo sapiens (Human) 
2024-08-23 | PXD044156 | Pride
During our efforts to isolate potantial binding partners of Esat6, we isolated few peptides rich in phenylalanine residues that strongly interacted with Esat6. All peptides were less than fifty amino acids in length, One of them, Hcl1, when expressed in mycobacteria showed significant retardation in...
ORGANISM(S): Mycobacterium tuberculosis 
Full transcriptome analysis of the mechanism of tuberculosis ESAT6-Fc2a in alleviating allergic asthma in mice
In the early stage, an OVA-induced mouse allergic asthma model was constructed and treated with ESAT6-Fc2a fusion protein, which proved that ESAT6-Fc2a fusion protein could reduce the infiltration of inflammatory cells in the lungs and had a therapeutic effect on asthma. In order to further explore ...
ORGANISM(S): Mus musculus 
2025-06-05 | GSE274427 | GEO
THP-1 macrophages response to ESAT6 stimulation_ Raw sequence reads
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