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TranscriptomicsExpression data comparing KYSE-140 ESCC cell line CD90+ and CD90- cells
To identify candidate genes involved in enhanced tumorigenicity and metastasis of CD90+ esophageal tumor-initiating cells. The esophageal squamous carcinoma cell (ESCC) cell line KYSE-140 was sorted into CD90+ and CD90- populations by flow cytometry. Total RNA was analyzed on Affymetrix Human Genome...
ORGANISM(S): Homo sapiens 
2013-03-23 | E-GEOD-37949 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation analysis of esophageal squamous cell carcinoma
Genome-wide methylation analysis was performed by methylated DNA immunoprecipitation-CGI microarray analysis. A pool of four cancer samples without lymph node metastasis, two pools of four cancer samples with lymph node metastasis, and three metastatic lymph nodes were prepared from the patients, an...
ORGANISM(S): Homo sapiens 
2010-12-21 | E-GEOD-21238 | biostudies-arrayexpress
ProteomicsQuantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke Schistosoma mansoni C4PR_LIV
Schistosomes are blood-dwelling helminth parasites causing a debilitating disease in the tropics. Major challenges to control persist and vaccines would provide an additional tool, but finding protective antigens is not trivial. It's known that the self-cure response of Rhesus macaques targets prote...
ORGANISM(S): Schistosoma mansoni 
2024-06-20 | PXD037384 | Pride
Microexon genes Schistosoma mansoni Esophageal gland 
ProteomicsQuantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke Schistosoma mansoni C4PR_LIV
Schistosomes are blood-dwelling helminth parasites causing a debilitating disease in the tropics. Major challenges to control persist and vaccines would provide an additional tool, but their development has been problematic. During the self-cure response of Rhesus macaques, antibodies target protein...
ORGANISM(S): Schistosoma mansoni (Blood fluke) 
2019-12-11 | PXD014872 | Pride
Microexon genes Esophageal gland Quantitative proteomics Schistosoma mansoni Gastrodermis 
ProteomicsAbsolute Quantification of Schistosoma mansoni Esophageal Gland Products
Schistosomes are blood-dwelling helminth parasites causing a debilitating disease in the tropics. Major challenges to control the disease persist and vaccines would provide an additional tool, but their development has been problematic. Rhesus macaques can self-cure following schistosome infection, ...
ORGANISM(S): Schistosoma Mansoni 
2019-11-22 | PXD014899 | panorama
TranscriptomicsDKK1 expression is down-regulated in the lymph node pre-metastatic niche in esophageal cancer
Lymph node metastasis is a poor prognosis indicator in esophageal cancer. Although tumor spreading currently forms the main basis for therapy selection, the molecular mechanisms underlying the metastatic pathway remain insufficiently understood. Several studies aimed to investigate these mechanisms ...
ORGANISM(S): Homo sapiens 
2015-05-18 | E-GEOD-51021 | biostudies-arrayexpress
TranscriptomicsNOTCH3 knockdown in non-transformed human esophageal cells
To determine the role of NOTCH3 in human esophageal epitheila homeostasis/squamous cell differentiation Zinc finger E-box binding (ZEB) proteins ZEB1 and ZEB2 are transcription factors essential in transforming growth factor (TGF)-β-mediated epithelial to mesenchymal transition (EMT), senescence an...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-27424 | biostudies-arrayexpress
UnknownThe esophageal gland mediates host immune evasion by the human parasite Schistosoma mansoni.
Not available
S-EPMC7431036 | biostudies-literature
UnknownSchistosome esophageal gland factor MEG-8.2 drives host cell lysis and interacts with host immune proteins.
Not available
S-EPMC11601278 | biostudies-literature
TranscriptomicsThe Diagnostic Value of Salivary microRNA in Esophageal Cancer
Tissue microRNAs (miRNAs) can detect cancers and predict prognosis. Several recent studies reported that tissue, plasma, and saliva miRNAs share similar expression profiles. In this study, we investigated the diagnostic value of salivary miRNAs (including whole saliva and saliva supernatant) for det...
ORGANISM(S): Homo sapiens 
2012-10-03 | E-GEOD-41268 | biostudies-arrayexpress
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