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TranscriptomicsTranscriptional profiling by array of pancreatic ductal adenocarcinoma xenograft models
We generated novel patient derived xenograft (PDX) and cell line -derived xenograft models for pancreatic ductal adenocarcinoma (PDAC) which reflect different molecular subtypes. Pancreatic ductal adenocarcinoma is currently the tumor with the fourth highest mortality rate. Recently, subtypes of PDA...
ORGANISM(S): Homo sapiens 
2016-01-12 | E-MTAB-4029 | biostudies-arrayexpress
TranscriptomicsExpression data from Epithelial colon cancer cells treated with TGF-beta
Most available CRC cell lines have lost their TGF-beta response through the acquisition of mutations either in TGF-beta type II receptor (TGFBR2) or the intracellular mediator SMAD4 (Reviewed in Markowitz et al. 2002). To study the effect of TGF-beta in CRC epithelial cells, we restored wild-type TG...
ORGANISM(S): Homo sapiens 
2014-09-08 | E-GEOD-59771 | biostudies-arrayexpress
TranscriptomicsExpression profiles of cell populations purified from human CRC (3 ways)
The survival of isolated metastatic cells and expansion into macroscopic tumour has been recognized as a limiting step for metastasis formation in several cancer types yet the determinants of this process remain largely uncharacterized. In colorectal cancer (CRC), we identify a transcriptional progr...
ORGANISM(S): Homo sapiens 
2013-01-17 | E-GEOD-39395 | biostudies-arrayexpress
TranscriptomicsExpression profiles of cell populations purified from human CRC (4 ways)
The survival of isolated metastatic cells and expansion into macroscopic tumour has been recognized as a limiting step for metastasis formation in several cancer types yet the determinants of this process remain largely uncharacterized. In colorectal cancer (CRC), we identify a transcriptional progr...
ORGANISM(S): Homo sapiens 
2013-01-17 | E-GEOD-39396 | biostudies-arrayexpress
TranscriptomicsExpression data from fibroblasts treated with TGF-Beta
The survival of isolated metastatic cells and expansion into macroscopic tumour has been recognized as a limiting step for metastasis formation in several cancer types yet the determinants of this process remain largely uncharacterized. In colorectal cancer (CRC), we identify a transcriptional progr...
ORGANISM(S): Homo sapiens 
2013-01-17 | E-GEOD-39394 | biostudies-arrayexpress
TranscriptomicsHuman CRC cell populations
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-01-17 | E-GEOD-39397 | biostudies-arrayexpress
UnknownHuman Retrotransposons and the Global Shutdown of Homeostatic Innate Immunity by Oncolytic Parvovirus H-1PV in Pancreatic Cancer.
Not available
S-EPMC8228339 | biostudies-literature
TranscriptomicsRNA-seq analysis of primary human cancer associated fibroblasts isolated from breast cancer tissue
Primary human cancer associated fibroblasts (CAFs) were isolated and cultivated (up to passage 10). CAFs were sequenced to find differences in their respective gene expression patters.
ORGANISM(S): Homo sapiens 
2021-02-03 | E-MTAB-10075 | biostudies-arrayexpress
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