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ProteomicsThe intracellular free concentration of EDCs enables successful translation between cell-free and cell-based estrogenic activity assays
Many environmental toxicants can activate the estrogen receptor α (ERα), contributing to disruption of normal endocrine function. Although these activities are known from in silico, in vitro and in vivo models, transferring the active concentrations between the different models is often challenging....
ORGANISM(S): Homo sapiens (Human) 
2025-07-31 | PXD059544 | Pride
In vitro Endocrine-disrupting chemicals Estrogenic chemicals Intracellular free concentration 
TranscriptomicsTranscriptomic effects of endocrine disruptors in zebrafish embryos
The identification of endocrine disruptive properties of chemicals certain to enter the aquatic environment relies on toxicity tests with fish, assessing adverse effects on reproduction and sexual development. The demand for quick, reliable endocrine disruption (ED) assays favored the use of fish em...
ORGANISM(S): Danio rerio 
2014-03-06 | E-GEOD-44263 | biostudies-arrayexpress
UnknownUltrasensitive Electrochemical Biosensor for Rapid Screening of Chemicals with Estrogenic Effect.
Not available
S-EPMC11430529 | biostudies-literature
UnknownAdditive mixture effects of estrogenic chemicals in human cell-based assays can be influenced by inclusion of chemicals with differing effect profiles.
Not available
S-EPMC3422259 | biostudies-literature
GenomicsIn vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals
In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals
PRJNA869442 | ENA
UnknownDevelopment of phenotypic and transcriptional biomarkers to evaluate relative activity of potentially estrogenic chemicals in ovariectomized mice.
Not available
S-EPMC4383572 | biostudies-literature
UnknownNovel Estrogen Receptor Dimerization BRET-Based Biosensors for Screening Estrogenic Endocrine-Disrupting Chemicals.
Not available
S-EPMC10923609 | biostudies-literature
UnknownDevelopment of a recombinant human ovarian (BG1) cell line containing estrogen receptor α and β for improved detection of estrogenic/antiestrogenic chemicals.
Not available
S-EPMC4772679 | biostudies-literature
UnknownAroER tri-screen™ is a novel functional assay to estimate both estrogenic and estrogen precursor activity of chemicals or biological specimens.
Not available
S-EPMC4591046 | biostudies-literature
UnknownThe in vitro estrogenic activities of polyfluorinated iodine alkanes.
Not available
S-EPMC3261944 | biostudies-literature
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