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TranscriptomicsGene expression and copy number analysis of OVCAR-3 and CDK2 resistant sublines
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-48921 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of OVCAR-3 and CDK2 resistant sublines
Cyclin E1 (CCNE1) is amplified in various tumor types including high-grade serous ovarian cancer where it is associated with poor clinical outcome. We have demonstrate that suppression of the Cyclin E1 partner kinase, CDK2, induces apoptosis in a CCNE1 amplicon-dependent manner. Little is known of m...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-48919 | biostudies-arrayexpress
TranscriptomicsCopy number analysis of OVCAR-3 and CDK2 resistant sublines
Cyclin E1 (CCNE1) is amplified in various tumor types including high-grade serous ovarian cancer where it is associated with poor clinical outcome. We have demonstrate that suppression of the Cyclin E1 partner kinase, CDK2, induces apoptosis in a CCNE1 amplicon-dependent manner. Little is known of m...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-48920 | biostudies-arrayexpress
TranscriptomicsGenomic analysis of low-grade serous ovarian carcinomas [ILOEF]
Low-grade serous ovarian carcinomas are typically Ras-pathway mutated, TP53 wild-type, have limited chromosomal aberration, and are frequently associated with borderline tumors. By contrast, high-grade serous ovarian carcinoma lack Ras-pathway mutations, are invariably TP53 mutated, show widespread ...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-57276 | biostudies-arrayexpress
TranscriptomicsGenomic analysis of low-grade serous ovarian carcinomas [IL610Q]
Low-grade serous ovarian carcinomas are typically Ras-pathway mutated, TP53 wild-type, have limited chromosomal aberration, and are frequently associated with borderline tumors. By contrast, high-grade serous ovarian carcinoma lack Ras-pathway mutations, are invariably TP53 mutated, show widespread ...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-57279 | biostudies-arrayexpress
TranscriptomicsGenomic analysis of low-grade serous ovarian carcinomas [EXP]
Low-grade serous ovarian carcinomas are typically Ras-pathway mutated, TP53 wild-type, have limited chromosomal aberration, and are frequently associated with borderline tumors. By contrast, high-grade serous ovarian carcinoma lack Ras-pathway mutations, are invariably TP53 mutated, show widespread ...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-56443 | biostudies-arrayexpress
TranscriptomicsGenomic analysis of low-grade serous ovarian carcinomas [ILOE]
Low-grade serous ovarian carcinomas are typically Ras-pathway mutated, TP53 wild-type, have limited chromosomal aberration, and are frequently associated with borderline tumors. By contrast, high-grade serous ovarian carcinoma lack Ras-pathway mutations, are invariably TP53 mutated, show widespread ...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-57270 | biostudies-arrayexpress
Genomicsc206f97a-4770-4337-a7bd-0bf63eede603 - samples
Whole-exome sequencing dataset for the Australian Ovarian Cancer Study (AOCS) and The Jikei University School of Medicine (JIKEI) ovarian clear cell carcinoma (OCCC) clinical outliers project, representing 10 donors. Consists of 20 fastq files: one normal and one tumour from each patient.
EGAD00001006004 | EGA
GenomicsWhole-exome sequencing of ovarian clear cell carcinoma in clinical outliers
Whole-exome sequencing dataset for the Australian Ovarian Cancer Study (AOCS) and The Jikei University School of Medicine (JIKEI) ovarian clear cell carcinoma (OCCC) clinical outliers project, representing 10 donors. Although OCCC are commonly resistant to platinum based chemotherapy, good clinical ...
EGAS00001004248 | EGA
GenomicsPeter MacCallum Cancer Centre Research Data Access Committee
Data Access Committee EGAC00001001500
EGAC00001001500 | EGA
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