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MetabolomicsMetabolomics reveals molecular signatures for psoriasis biomarkers and drug targets discovery
Psoriasis is a chronic skin disease that affects multiple systems and can be influenced by immunological, environmental, and genetic factors. The discovery of plasma biomarkers of psoriasis and the regulation of metabolic pathways helps us understand psoriasis and may assist clinicians in the diagno...
2024-09-26 | MTBLS5185 | MetaboLights
MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
MetabolomicsDiagnostic metabolite biomarkers of chronic typhoid carriage
Background: Salmonella Typhi and Salmonella Paratyphi A are the agents of enteric (typhoid) fever; both can establish chronic carriage in the gallbladder. Chronic Salmonella carriers are typically asymptomatic, intermittently shedding bacteria in the feces, and contributing to disease transmission. ...
2018-01-17 | MTBLS579 | MetaboLights
MetabolomicsFecal Metabolomics and Potential Biomarkers for Systemic Lupus Erythematosus
The role of metabolomics in autoimmune diseases has been a rapidly expanding area in researches over the last decade, while its pathophysiologic impact on systemic lupus erythematosus (SLE) remains poorly elucidated. In this study, we analyzed the metabolic profiling of fecal samples from SLE patien...
2020-01-30 | MTBLS916 | MetaboLights
MetabolomicsUPLC-QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis
Identification of new biomarkers may help in the early diagnosis of inflammatory bowel disease (IBD). In this study, ultrahigh-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS) was used to analyze the untargeted lipidomics and compare plasma l...
2021-10-18 | MTBLS1183 | MetaboLights
MetabolomicsIdentification of Biomarkers Using Metabolomics: From Chronic Non-Atrophic Gastritis and Chronic Atrophic Gastritis to Gastric Cancer

Gastric cancer (GC) is a severe malignancy characterized by late diagnosis, poor prognosis and low survival rates. Its progression is often linked to chronic non-atrophic gastritis (CNAG) and chronic atrophic gastritis (CAG), which show atypical symptoms. Identifying biomarkers for CNAG, CAG and ...

2026-09-29 | MTBLS12186 | MetaboLights
MetabolomicsMapping of the viral shunt across widespread coccolithophore blooms using metabolic biomarkers

The viral shunt is a fundamental ecosystem process which diverts the flux of organic carbon fixed through photosynthesis during algal bloom events from heterotrophic grazers to bacteria. Through the extracellular release of metabolites, lytic viral infections supply 2-10% of photosynthetically fi...

2025-10-08 | MTBLS11597 | MetaboLights
MetabolomicsAltered fecal metabolomics and potential biomarkers of psoriatic arthritis differing from rheumatoid arthritis
Psoriatic arthritis (PsA) is a chronic inflammatory joint disease, and the diagnosis is quite difficult due to the unavailability of reliable clinical markers. This study aimed to investigate the fecal metabolites in PsA by comparison with rheumatoid arthritis (RA), and to identify potential diagnos...
2022-02-23 | MTBLS4206 | MetaboLights
MetabolomicsSerum untargeted metabolomics reveals distinct metabolic signatures and potential biomarkers in female and latent genital tuberculosis

Female genital tuberculosis (FGTB) and latent genital tuberculosis (LGTB) critically impair women's reproductive health. However, their early diagnosis and treatment remain challenging due to nonspecific symptoms and suboptimal diagnostic methods. This study utilized serum untargeted metabolomics...

2025-12-25 | MTBLS12319 | MetaboLights
MetabolomicsExploratory metabolomic profiling in migraine with PFO: dysregulated pathways and potential biomarkers

Background: Emerging evidence implicates patent foramen ovale (PFO) as a potential contributor to migraine through paradoxical metabolite shunting, microembolism and hypoxemia. However, systematic characterization of metabolic alterations in migraine patients with PFO (PFO-M) remains un...

2026-03-26 | MTBLS13630 | MetaboLights
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