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MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
MetabolomicsSerum untargeted metabolomics reveals distinct metabolic signatures and potential biomarkers in female and latent genital tuberculosis

Female genital tuberculosis (FGTB) and latent genital tuberculosis (LGTB) critically impair women's reproductive health. However, their early diagnosis and treatment remain challenging due to nonspecific symptoms and suboptimal diagnostic methods. This study utilized serum untargeted metabolomics...

2025-12-25 | MTBLS12319 | MetaboLights
MetabolomicsUrinary metabolomic profiling to identify biomarkers of a flavonoid-rich and flavonoid-poor fruits and vegetables diet in adults: the FLAVURS trial
The present study aims to investigate the dose dependent effects of consuming diets enriched in flavonoid-rich and flavonoid-poor fruits and vegetables on the urine metabolome of adults who had a ≥1.5 fold increased risk of cardiovascular diseases. A single-blind, dose-dependent, parallel randomized...
2017-01-19 | MTBLS198 | MetaboLights
UnknownSimultaneous Isolation of Circulating Nucleic Acids and EV-Associated Protein Biomarkers From Unprocessed Plasma Using an AC Electrokinetics-Based Platform.
Not available
S-EPMC7674311 | biostudies-literature
Proteomics: Seminal Extracellular Vesicles – A New Frontier in Biomarker Discovery Through Protocol Optimization
: Seminal extracellular vesicles (EVs) hold a promise as a source of biomarkers for urogenital diseases. Unlocking their potential in clinical research requires further investigation to optimize the isolation protocols of these vesicles from semen. This study compares different isolation techniques ...
ORGANISM(S): Homo sapiens (Human) 
2026-10-26 | PXD069636 | Pride
Exosomes Extracellular vesicles Ev isolation : seminal fluid Ev-based biomarkers 
ProteomicsLineage specific extracellular vesicle-associated protein biomarkers for the early detection of high grade serous ovarian cancer
High grade serous ovarian carcinoma (HGSOC) accounts for ~70% of ovarian cancer cases. Non-invasive, highly specific blood-based tests for pre-symptomatic screening in women are crucial to reducing the mortality associated with this disease. Since most HGSOCs typically arise from the fallopian tubes...
ORGANISM(S): Homo sapiens (Human) 
2023-10-09 | PXD036726 | Pride
Exosomes High grade serous Extracellular vesicles Ovarian cancer Fallopian tube Early detection Biomarkers 
ProteomicsPlasma EVs-Derived Complement Proteins as Biomarkers of Sarcopenia Progression in Longitudinal Cohorts
Sarcopenia is characterized by progressive loss of muscle mass, strength, and physical performance, yet current diagnostic tools are limited for practical and longitudinal monitoring. To explore alternative biomarkers, we performed quantitative proteomic profiling of plasma-derived extracellular ves...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD073288 | Pride
extracellular vesicles Sarcopenia Biomarkers Aging Complement proteins 
ProteomicsProteomic Profile of Urinary Extracellular Vesicles Unravelled Biomarkers for Prostate Cancer Recognition
Proteomic profiling of extracellular vesicles (EVs) represents a promising approach for early detection and therapeutic monitoring of diseases such as cancer, which was aimed for identifying novel biomarkers for prostate cancer diagnosis in this study. The focus of this study was to develop a robust...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037506 | Pride
Extracellular vesicles Prostate cancer Biomarkers 
ProteomicsPlasma-derived extracellular vesicles contain predictive biomarkers and potential therapeutic targets for myocardial ischemic injury
Myocardial infarction (MI), an undesirable clinical outcome of coronary artery disease (CAD), triggers a potent inflammatory response via the release of circulatory mediators, including extracellular vesicles (EVs) by damaged cardiac cells, which is necessary for myocardial healing. However, when in...
ORGANISM(S): Homo sapiens (Human) 
2016-05-31 | PXD002950 | Pride
Cardiovascular disease  exosomes  label-free quantification  plasma or serum analysis  biomarker: diagnostic  extracellular vesicles 
UnknownProteomic-based identification of novel EV-derived protein antibodies biomarkers for melioidosis diagnosis.
Not available
S-EPMC12459824 | biostudies-literature
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