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TranscriptomicsTranscription profiling of human Ewing sarcoma samples and EWS-FLI-1 inhibited Ewing sarcoma cell lines
The cellular origin of Ewing tumor (ET), a tumor of bone or soft tissues characterized by specific fusions between EWS and ETS genes, is highly debated. Through gene expression analysis comparing ETs with a variety of normal tissues, we show that the profiles of different EWS-FLI1-silenced Ewing cel...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7007 | biostudies-arrayexpress
ProteomicsHuman A673 Ewing sarcoma secretome - effect of EWS-FLI-1 silencing
EWS-FLI-1 was silenced by an shRNA in A673 Ewing sarcoma cells and the resulting alterations in the secretome was analyzed by GeLC-MS/MS approach (six gel slices for each sample, luciferase shRNA-expressing cell secretome as control)
ORGANISM(S): Homo sapiens (Human) 
2021-07-06 | PXD016052 | Pride
Ewing sarcoma Ews-fli-1 Gelc-ms/ms Secretome 
UnknownThe role of FLI-1-EWS, a fusion gene reciprocal to EWS-FLI-1, in Ewing sarcoma.
Not available
S-EPMC4701224 | biostudies-literature
TranscriptomicsGene expression analysis of human pediatric mesenchymal stem cells (hpMSCs) upon expression of EWS-FLI-1
Cancer stem cells (CSCs) display plasticity and self-renewal properties reminiscent of normal tissue stem cells, but the events responsible for their emergence remain obscure. We recently identified CSCs in Ewing sarcoma family tumors (ESFTs) and showed that they retain mesenchymal stem cell (MSC) p...
ORGANISM(S): Homo sapiens 
2011-08-04 | E-GEOD-31215 | biostudies-arrayexpress
GenomicsTranscriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1]
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1]
PRJNA505501 | ENA
UnknownEWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice.
Not available
S-EPMC2169157 | biostudies-literature
UnknownEWS-FLI-1 creates a cell surface microenvironment conducive to IGF signaling by inducing pappalysin-1.
Not available
S-EPMC5755722 | biostudies-literature
UnknownLet-7a is a direct EWS-FLI-1 target implicated in Ewing's sarcoma development.
Not available
S-EPMC3154507 | biostudies-literature
TranscriptomicsRNA immunoprecipitation (RIP)-Chip analysis for EWS-bound mRNA
Although EWS/FLI-1 fusion protein is responsible for most EwingM-bM-^@M-^Ys sarcoma family tumors (ESFT), the function of native EWS remains largely unknown. Here, we first showed that EWS repressed protein expression in a tethering assay. mRNAs bound to EWS were determined by RNA-immunoprecipitatio...
ORGANISM(S): Homo sapiens 
2012-01-16 | E-GEOD-29313 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of human pediatric mesenchymal stem cells (hpMSCs) upon expression of EWS-FLI-1
Cancer stem cells (CSCs) display plasticity and self-renewal properties reminiscent of normal tissue stem cells, but the events responsible for their emergence remain obscure. We recently identified CSCs in Ewing sarcoma family tumors (ESFTs) and showed that they retain mesenchymal stem cell (MSC) p...
ORGANISM(S): Homo sapiens 
2011-08-05 | GSE31215 | GEO
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