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MetabolomicsDelayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle

Exercise is fundamental to healthy aging, yet the degree to which it mitigates age-related molecular changes and how varying physical fitness levels influence the molecular response to exercise with age remain unclear. To address this, we performed transcriptomics, lipidomics, and metabolomics on...

2026-04-09 | MTBLS12824 | MetaboLights
MetabolomicsExercise Activates Interferon Immune Response of the Liver via Gpld1 to Enhance Antiviral Innate Immunity

Healthy behavioral patterns could modulate organ functions to enhance the body’s immunity. However, whether exercise regulates antiviral innate immunity remains elusive. Here, we found that exercise promotes type-I IFN (IFN-I) production in the liver and enhances IFN-I immune activity of the body...

2024-04-24 | MTBLS7972 | MetaboLights
MetabolomicsAcute metabolomic changes of plasma in response to endurance exercise
Not available
ORGANISM(S): Homo sapiens 
ST001789 | MetabolomicsWorkbench
MetabolomicsChanges in the metabalome and lipidome in response to exercise training
Not available
ORGANISM(S): Homo sapiens 
ST000387 | MetabolomicsWorkbench
TranscriptomicsSkeletal muscle gene expression in response to resistance exercise: sex specific regulation
The molecular mechanisms underlying the sex differences in human muscle morphology and function remain to be elucidated. The purpose of the study was to detect the sex differences in the skeletal muscle transcriptome in both the resting state and following anabolic stimuli, resistance exercise. We u...
ORGANISM(S): Homo sapiens 
2010-12-06 | E-GEOD-24235 | biostudies-arrayexpress
TranscriptomicsChanges in the transcriptome of circulating neutrophils and skeletal muscle in response to endurance exercise
Analysis of the changes in the transcriptome of circulating neutrophils and skeletal muscle from standardized resting conditions (baseline; pre-EXTRI) to 3, 48 and 96 hours after an experimental exercise trial (EXTRI; 1 hour of cycling followed by 1 hours of running) in 8 healthy, endurance-trained,...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-GEOD-43856 | biostudies-arrayexpress
MetabolomicsUnderstanding the response to endurance exercise using a systems biology approach: combining blood metabolomics, transcriptomics and miRNome in horses
Not available
ORGANISM(S): Equus caballus 
ST000503 | MetabolomicsWorkbench
TranscriptomicsCytokines dominate the secretome of primary human myotubes in an in vitro exercise model
Muscle contraction during exercise is the major stimulus for the release of peptides and proteins (myokines) that are supposed to take part in the benefical adaptation to exercise. We hypothesize that application of an in vitro exercise stimulus as electric pulse stimulation (EPS) to human myotubes ...
ORGANISM(S): Homo sapiens 
2013-10-09 | E-GEOD-44051 | biostudies-arrayexpress
TranscriptomicsDynamics of the human skeletal muscle transcriptome in response to exercise training - part 1
A total of 23 participants (data available in present submission and in GSE58608) completed three months of supervised aerobic exercise training of one leg. Skeletal muscle biopsies have been collected before and after the training period. We have investigated differences between trained and untrain...
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-60590 | biostudies-arrayexpress
TranscriptomicsHuman skeletal muscle transcriptional response to exercise
The aim of this investigation was to evaluate the effect of training on the global transcriptional response of skeletal muscle to an acute bout of resistance exercise. Seven young healthy men and women underwent a 12-week supervised progressive unilateral arm resistance exercise (RE) training progra...
ORGANISM(S): Homo sapiens 
2011-12-15 | E-GEOD-28998 | biostudies-arrayexpress
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