Sort   by:  
 Page size 
ProteomicsDepletion of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication
New therapeutic targets are a valuable resource in the struggle to reduce the morbidity and mortality associated with the COVID-19 pandemic. Genome-wide association studies (GWAS) have identified a number of risk loci but these include co-morbidities and are not specific to host-virus interactions. ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD031611 | Pride
Sars-cov-2 Viral replication Exosc2 
GenomicsAging-dependent dysregulation of EXOSC2 is maintained in cancer as a dependency
Aging-dependent dysregulation of EXOSC2 is maintained in cancer as a dependency
PRJNA976202 | ENA
UnknownLow expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
Not available
S-EPMC9585911 | biostudies-literature
UnknownLow expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
Not available
S-EPMC8923113 | biostudies-literature
TranscriptomicsAging-dependent dysregulation of EXOSC2 is maintained in cancer as a dependency
Reprogramming of aged donor tissue cells into induced pluripotent stem cells (A-iPSC) preserved the epigenetic memory of original aged-donor tissue, defined as genomic instability and poor tissue differentiation in our previous study. The unbalanced expression of RNA exosome subunits affects the RNA...
ORGANISM(S): Mus musculus 
2025-12-20 | GSE233404 | GEO
GenomicsA Budding Yeast Model for Human Disease Mutations in the EXOSC2 Cap Subunit of the RNA Exosome
A Budding Yeast Model for Human Disease Mutations in the EXOSC2 Cap Subunit of the RNA Exosome
PRJNA684912 | ENA
UnknownA budding yeast model for human disease mutations in the EXOSC2 cap subunit of the RNA exosome complex.
Not available
S-EPMC8370739 | biostudies-literature
TranscriptomicsA Budding Yeast Model for Human Disease Mutations in the EXOSC2 Cap Subunit of the RNA Exosome
RNA exosomopathies, a growing family of tissue-specific diseases, are linked to missense mutations in genes encoding the structural subunits of the conserved 10-subunit exoribonuclease complex, the RNA exosome. Such mutations in the cap subunit gene EXOSC2 cause the novel syndrome SHRF (Short statur...
ORGANISM(S): Saccharomyces cerevisiae 
2020-12-14 | GSE163106 | GEO
UnknownGenetic and genomic studies of pathogenic EXOSC2 mutations in the newly described disease SHRF implicate the autophagy pathway in disease pathogenesis.
Not available
S-EPMC7068030 | biostudies-literature
Genomics
"XRNAX-CLIP-seq on MCF7 cells for LMNB1 and EXOSC2"
PRJEB26442 | ENA
Sort   by:  
 Page size