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MetabolomicsHippophae rhamnoides-Derived Exosome-like Nanovesicles Alleviate Dexamethasone-Induced Sarcopenia by Remodeling Skeletal Muscle Lipid Metabolism
Skeletal muscle atrophy driven by glucocorticoid excess is a clinically relevant contributor to sarcopenia, yet safe and biologically integrated interventions remain limited. Here we report that extracellular exosome-like nanovesicles derived from Hippophae rhamnoides fruits (HR-ELNs) protect agains...
2026-07-17 | MTBLS15070 | MetaboLights
MetabolomicsLC-MS lipidomic characterization of plant-derived exosome-like nanovesicles from ginseng, pueraria lobata, and Chinese yam

This study characterizes the lipid composition of exosome-like nanovesicles isolated from Ginseng, Pueraria lobata, and Chinese yam using LC-MS-based lipidomics. The dataset includes LC-MS raw data and processed lipid annotation and relative quantification tables acquired in both positive and neg...

2026-07-27 | MTBLS14935 | MetaboLights
TranscriptomicsExpression data from Drosophila S2 cells depleted of exosome subunits
The exosome complex and its' subunits are vital for proccessing and or degrading many cellular RNAs. We used microarrays to detail the global changes in mRNA levels in response to exosome subunit depletion. RNA was extracted from dsRNA treated S2 cells and hybridized using Affymetrix microarrays. We...
ORGANISM(S): Drosophila melanogaster 
2010-04-12 | E-GEOD-17874 | biostudies-arrayexpress
TranscriptomicsGenome-wide localization of exosome components to active promoters and chromatin insulators in Drosophila
Chromatin insulators are functionally conserved DNA-protein complexes that are situated throughout the genome and organize independent transcriptional domains.  Previous work implicated RNA as an important cofactor in chromatin insulator activity, although the mechanisms by which RNA affects insulat...
ORGANISM(S): Drosophila melanogaster 
2013-01-29 | E-GEOD-41950 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of thermosensitive exosome mutants from permissive temperature and various time exposure to restrictive temperature
Transcriptome analyses of thermosensitive exosome mutants from permissive temperature to various time exposure to restrictive temperature.
ORGANISM(S): Saccharomyces cerevisiae 
2006-02-28 | E-MEXP-537 | biostudies-arrayexpress
TranscriptomicsTranscriptome-wide Analysis of Exosome Targets in the Budding Yeast Saccharomyces cerevisiae
Purpose: The exosome plays major roles in RNA processing and surveillance but the in vivo target range and substrate acquisition mechanisms remain unclear. We applied an in vivo cross-linking technique coupled with deep sequencing (CRAC) that captures transcriptome-wide interactions between individu...
ORGANISM(S): Saccharomyces cerevisiae 
2012-09-25 | E-GEOD-40046 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and extracellular (exosomal) miRNAs in hypoxic RPMI8226 cells
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-45388 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and extracellular (exosomal) miRNAs in hypoxic K562 cells
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-45289 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and extracellular (exosomal) miRNAs in hypoxic SUDHL4 cells
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-45387 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and exosomal miRNAs in hypoxia-resistant KMS-11 cells
In multiple myeloma (MM), abnormal plasma cells interact with bone marrow (BM) stromal cells and vascular cells among others. A part of the BM milieu is considered highly hypoxic, and myeloma cells in situ may be influenced by circumstances other than normoxia in vitro. Hence, we attempted to confir...
ORGANISM(S): Homo sapiens 
2014-10-15 | E-GEOD-48908 | biostudies-arrayexpress
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