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ProteomicsDeficiency of THSD7A reverses glomerular proteomic profiles in anti-THSD7A antibody induced membranous nephropathy models
Proteomics experiment 3/3 associated with this work. THSD7A is a key podocyte antigen in membranous nephropathy (MN), an antibody-mediated autoimmune disease. While the pathogenic role of autoantibodies targeting THSD7A in MN is well described, the consequences of autoantibody binding for podocyte h...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-30 | PXD065344 | Pride
Anti-thsd7a antibody induced membranous nephropathy Podocyte injury Experimental membranous nephropathy 
GenomicsFunctional characterization of podocyte-expressed THSD7A in experimental membranous nephropathy
Functional characterization of podocyte-expressed THSD7A in experimental membranous nephropathy
PRJNA1279978 | ENA
UnknownObinutuzumab and Ofatumumab are More Effective Than Rituximab in the Treatment of Membranous Nephropathy Patients With Anti-Rituximab Antibodies.
Not available
S-EPMC11993203 | biostudies-literature
ProteomicsProteomic analysis of glomeruli from Thsd7a podocyte knockout and WT mice
Proteomics experiment 1/3 associated with this work. THSD7A is a key podocyte antigen in membranous nephropathy (MN), an antibody-mediated autoimmune disease. While the pathogenic role of autoantibodies targeting THSD7A in MN is well described, the consequences of autoantibody binding for podocyte h...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-30 | PXD065322 | Pride
Podocyte injury Experimental membranous nephropathy Podocyte-specific knockout of thsd7a 
ProteomicsTHSD7A interactome in native mouse glomeruli
Proteomics experiment 2/3 associated with this work. THSD7A is a key podocyte antigen in membranous nephropathy (MN), an antibody-mediated autoimmune disease. While the pathogenic role of autoantibodies targeting THSD7A in MN is well described, the consequences of autoantibody binding for podocyte h...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-30 | PXD065323 | Pride
Ap-ms Interactome of thsd7a Podocyte injury Co-ip Experimental membranous nephropathy 
TranscriptomicsFunctional characterization of podocyte-expressed THSD7A in experimental membranous nephropathy
Although the pathogenic role of autoantibodies targeting the podocyte protein THSD7A in membranous nephropathy (MN) is well described, the consequences of autoantibody binding for podocyte homeostasis and the function of THSD7A remain unclear. Here, we induced an MN model in control and podocyte-spe...
ORGANISM(S): Mus musculus 
2026-02-02 | GSE300256 | GEO
UnknownAdvances of the experimental models of idiopathic membranous nephropathy (Review).
Not available
S-EPMC7115214 | biostudies-literature
UnknownIntegrative analysis of miRNA-mRNA network in idiopathic membranous nephropathy by bioinformatics analysis.
Not available
S-EPMC8487241 | biostudies-literature
UnknownAutoimmunity in membranous nephropathy targets aldose reductase and SOD2.
Not available
S-EPMC2831859 | biostudies-literature
UnknownCirculating Antibodies against Thrombospondin Type-I Domain-Containing 7A in Chinese Patients with Idiopathic Membranous Nephropathy.
Not available
S-EPMC5628706 | biostudies-literature
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