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ProteomicsAn Exported Kinase Family Mediates Species-Specific Erythrocyte Remodelling and Virulence in Human Malaria
The most severe form of human malaria is caused by Plasmodium falciparum. Its virulence is closely linked to the increase in rigidity and cytoadhesion of infected erythrocytes, which obstruct blood flow to vital organs. Unlike other human-infecting Plasmodium species, P. falciparum exports a family ...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum (isolate 3D7) Plasmodium knowlesi strain H 
2020-04-17 | PXD015833 | Pride
Plasmodium Fikk kinases Malaria Red blood cell Phosphorylation 
UnknownThe FIKK kinase of Toxoplasma gondii is not essential for the parasite's lytic cycle.
Not available
S-EPMC4844859 | biostudies-literature
UnknownThe fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound.
Not available
S-EPMC12137140 | biostudies-literature
UnknownAn exported kinase family mediates species-specific erythrocyte remodelling and virulence in human malaria.
Not available
S-EPMC7116245 | biostudies-literature
ProteomicsFIKK4.1-FIKK4.2 protein environment in Plasmodium falciparum infected red blood cells
In this project we used proximity labelling to investigate the environment of 2 P.falciparum kinases, FIKK4.1 and FIKK4.2, exported in the infected red blood cell (iRBCs), by fusing them to a biotin ligase. Peptide-level analysis was used to obtain more information about the topography of these 2 ki...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum NF54 
2025-05-20 | PXD048966 | Pride
Plasmodium falciparum Exported fikk kinases Peptide-level proximity labelling Lc-ms/ms 
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