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ProteomicsMELK mediates the stability of EZH2 throught site-specific phosphorylation in extranodal natural killer/T-cell lymphoma
Oncogenic EZH2 is overexpressed and extensively involved in the pathophysiology of different cancers including extranodal natural killer/T-cell lymphoma (NKTL). However, the mechanisms regarding EZH2 upregulation is poorly understood, and it still remains untargetable in NKTL. In this study, we exam...
ORGANISM(S): Homo sapiens (Human) 
2019-08-26 | PXD015008 | Pride
Melk Silac Ubiquitination Phosphorylation Extranodal natural killer/t-cell lymphoma (nktl) Ezh2 
TranscriptomicsmiRNA expression profiling of NKTCL (Natural Killer/T-Cell Lymphoma) samples
We performed a comprehensive genome-wide miRNA expression profiling (MEP) of extranodal nasal-type Natural Killer/T-cell lymphoma (NKTL) using formalin fixed paraffin-embedded tissue (FFPE) (n=30) and NK cell lines (n=6) in comparison with normal NK cells, with the objective of understanding the pat...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-31377 | biostudies-arrayexpress
TranscriptomicsGene expression of extranodal NK/T cell lymphoma I
Gene expression profiling of extranodal nasal-type NK/T cell lymphoma and other EBV-associated lymphoid proliferation disease patients was analyzed to elucidate association between JAK-STAT pathway and canonical or non-canonical PRC2/EZH2 target pathways using Illumina HumanRef-8 v3 chips. 6 samples...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-80629 | biostudies-arrayexpress
TranscriptomicsGene expression of extranodal NK/T cell lymphoma II
Gene expression profiling of extranodal nasal-type NK/T cell lymphoma and other EBV-associated lymphoid proliferation disease patients was analyzed to elucidate association between JAK-STAT pathway and canonical or non-canonical PRC2/EZH2 target pathways using Illumina HumanRef-8 v3 chips. In total,...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-80631 | biostudies-arrayexpress
GenomicsGenomic landscape and PD-1 blockade in Natural-killer/T cell lymphoma
Natural killer/T-cell lymphoma (NKTL) is an aggressive malignancy with a predilection for Asian, Mexican and South American populations. With the exception of Japan, it is the most common mature T-cell lymphoma in Asia. NKTL presents as extranodal disease and mostly affects the upper aerodigestive t...
EGAS00001003828 | EGA
GenomicsmiRNA expression profiling of NKTCL (Natural Killer/T-Cell Lymphoma) samples
We performed a comprehensive genome-wide miRNA expression profiling (MEP) of extranodal nasal-type Natural Killer/T-cell lymphoma (NKTL) using formalin fixed paraffin-embedded tissue (FFPE) (n=30) and NK cell lines (n=6) in comparison with normal NK cells, with the objective of understanding the pat...
ORGANISM(S): Homo sapiens 
2011-11-23 | GSE31377 | GEO
TranscriptomicsGene expression of extranodal NK/T cell lymphoma
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-80632 | biostudies-arrayexpress
UnknownRUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC.
Not available
S-EPMC5629367 | biostudies-literature
GenomicsHomo sapiens
miRNA expression profiling of NKTCL (Natural Killer/T-Cell Lymphoma) samples
PRJNA145905 | ENA
UnknownSerum-Derived Exosomal MicroRNA Profiles Can Predict Poor Survival Outcomes in Patients with Extranodal Natural Killer/T-Cell Lymphoma.
Not available
S-EPMC7761501 | biostudies-literature
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