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UnknownMitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.
Not available
S-EPMC3582741 | biostudies-literature
UnknownMolecular mechanisms promoting long-term cytopenia after BCMA CAR-T therapy in multiple myeloma.
Not available
S-EPMC11532743 | biostudies-literature
UnknownMMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC.
Not available
S-EPMC3886861 | biostudies-literature
UnknownMMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents.
Not available
S-EPMC6071667 | biostudies-literature
UnknownExpression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung.
Not available
S-EPMC4874209 | biostudies-literature
GenomicsMMSET alters EZH2 Binding in Myeloma Cells
We investigated EZH2 binding in the presence and absence of MMSET protein. MMSET overexpression in t(4;14)+ myeloma leads to global loss of H3K27 methylation and redistribution of EZH2 binding throughout the genome ChIP-seq for EZH2 in two cell types
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-57632 | biostudies-arrayexpress
UnknownSimiC enables the inference of complex gene regulatory dynamics across cell phenotypes.
Not available
S-EPMC9005655 | biostudies-literature
GenomicsMMSET Induces Global and Focal Changes in Histone Methylation in Myeloma Cells
We investigated genome wide distribution of H3K36me2, H3K36me3 and H3K27me3 in the presence and absence of MMSET protein. MMSET overexpression in t(4;14)+ myeloma leads to global loss redistribution of H3K36me2 and genome-wide loss of H3K27 methylation. Despite the gloal decrease in H3K27me3, speci...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-57977 | biostudies-arrayexpress
UnknownKDM6A regulates immune response genes in multiple myeloma.
Not available
S-EPMC11952010 | biostudies-literature
GenomicsDeregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape [ChIP-seq]
Unrestrained receptor tyrosine kinase (RTK) signaling and epigenetic deregulation are root causes of tumorigenesis. We establish linkage between these processes by demonstrating that aberrant RTK signaling unleashed by oncogenic HRasG12V or loss of negative feedback through Sprouty gene deletion rem...
ORGANISM(S): Mus musculus 
2015-08-22 | E-GEOD-64190 | biostudies-arrayexpress
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