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ProteomicsA SWATH LABEL-FREE PROTEOMICS INSIGHT INTO THE FAAH-/- MOUSE LIVER
Fatty acid amide hydrolase (FAAH) is an important enzyme for lipid metabolism and an interesting pharmacological target, given its role in anandamide breakdown. The FAAH-/- genotype is the most widely used mouse model to achieve complete abolition of this enzyme. In this paper we explore, by means ...
ORGANISM(S): Mus musculus (Mouse) 
2018-08-20 | PXD010087 | Pride
Faah Swath Liver proteomics 
ModelsBenson2014 - FAAH inhibitors for the treatment of osteoarthritic pain
Benson2014 - FAAH inhibitors for the treatment of osteoarthritic pain Evaluation of fatty acid amide hydrolase (FAAH) as a target for osteoarthritic pain in humans, using an integrated systems pharmacology model. The SBML version of the model is o...
2024-09-02 | BIOMD0000000512 | BioModels
GenomicsInhibition of vascular growth by modulation of the AEA/FAAH axis
Inhibition of vascular growth by modulation of the AEA/FAAH axis
PRJNA639708 | ENA
TranscriptomicsThe bile acid CoA ligase, FATP5, is necessary for NAT synthesis in the liver
This study aimed to investigate the overlap between hepatic NAT and the bile acid synthesis to identify additional enzymes involved in NAT synthesis in the liver. We sequenced livers high-fat fed mice the were either wild-type or with a single-amino acid substitution in fatty acid amide hydrolase (F...
ORGANISM(S): Mus musculus 
2026-03-02 | E-MTAB-15752 | biostudies-arrayexpress
TranscriptomicsInhibition of vascular growth by modulation of the AEA/FAAH axis
Inhibition of FAAH and AEA accumulation reduces angiogenesis.
ORGANISM(S): Homo sapiens 
2021-10-08 | GSE152552 | GEO
UnknownMolecular basis of FAAH-OUT-associated human pain insensitivity.
Not available
S-EPMC10473560 | biostudies-literature
UnknownFAAH inhibition ameliorates breast cancer in a murine model.
Not available
S-EPMC10624203 | biostudies-literature
UnknownThe endocannabinoid hydrolase FAAH is an allosteric enzyme.
Not available
S-EPMC7010751 | biostudies-literature
UnknownPreclinical Characterization of the FAAH Inhibitor JNJ-42165279.
Not available
S-EPMC4677372 | biostudies-literature
UnknownStructure-guided inhibitor design for human FAAH by interspecies active site conversion.
Not available
S-EPMC2529035 | biostudies-literature
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