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MetabolomicsVisceral obesity-Induced METTL27 regulation of the FABP5/PPARD/CPT1A axis in promoting colorectal cancer progression

The incidence of obesity and colorectal cancer (CRC) is rising annually. Obesity, particularly visceral obesity, poses a serious health threat, yet the association of obesity with CRC progression, as well as the role of visceral obesity, remains debated. This study analyzed 394 CRC patients ...

2025-10-06 | MTBLS13095 | MetaboLights
GenomicsHigh-throughput sequencing analysis of mouse FABP5 KO BMDM cell transcriptomes with overexpression of FABP5 WT or FABP5 C127S after LPS treatment
High-throughput sequencing analysis of mouse FABP5 KO BMDM cell transcriptomes with overexpression of FABP5 WT or FABP5 C127S after LPS treatment
PRJNA755440 | ENA
TranscriptomicsEffect of exogenous FABP4 (A-FABP/aP2) and FABP5 (E-FABP/mal1) on gene expression in adipocyte-derived stem cells (ADSC) and 233A cells
Gene expression profile of treatment with FABP4 or FABP5 in ADSC and 233A cells was examined. ADSC or 233A cells were treated with and without 1 µM recombinant FABP4 or FABP5.
ORGANISM(S): Homo sapiens 
2016-06-23 | E-GEOD-83587 | biostudies-arrayexpress
GenomicsModulation of Inflammatory Pain by Myeloid FABP5
Modulation of Inflammatory Pain by Myeloid FABP5
PRJNA1269064 | ENA
ProteomicsDehydroglutathione to induce glutathione modification in protein
Protein S-glutathionylation is one of the major cysteine oxidations regulating redox signaling and oxidative stress. In this study, we developed a glutathione-derived chemical tool, namely dehydroglutathione, that can introduce a non-reducible glutathionylation mimic to protein, which can be utilize...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD061319 | Pride
Glutathionylation Fabp5 Dehydroglutathione 
ProteomicsExosomal FABP5 Drives HCC Progression via Macrophage Lipid 1 Metabolism and Immune Microenvironment Remodeling
Introduction: The progression of hepatocellular carcinoma (HCC) is intricately linked to complex interactions within the tumor microenvironment (TME), where the reprogramming of tumor-associated macrophages (TAMs) plays a pivotal role. However, how HCC cells regulate TAM metabolism and function via ...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-12 | PXD068213 | Pride
Lipid metabolism Fatty acid-binding protein 5 Tumor-associated macrophages Exosomes Hepatocellular carcinoma 
GenomicsRepressed FABP5 expression or activity weakens the adaptive response to AKI
Repressed FABP5 expression or activity weakens the adaptive response to AKI
PRJNA1458186 | ENA
TranscriptomicsGene expression breast cancer
Gene expression profiles were generated from 176 primary breast cancer patients and 12 normal breast samples. This data is used to investigate the clinical relevance of genes of interest from in vitro studies, including FABP5 and DDX1. This Series represents RNA isolated from 176 primary breast canc...
ORGANISM(S): Homo sapiens 
2011-04-27 | E-GEOD-22820 | biostudies-arrayexpress
TranscriptomicsHigh-throughput sequencing analysis of mouse FABP5 KO BMDM cell transcriptomes with overexpression of FABP5 WT or FABP5 C127S after LPS treatment
Purpose: Mouse BMDM is the universal cell type of studying innate immunity. This study was designed to analyze LPS induced innate immune response and the gene expression in FABP5 KO BMDMs with overexpression of FABP5 WT or FABP5 C127S. Methods: FABP5 KO BMDMs were nucleofected with 5 μg pXJ40-3xFlag...
ORGANISM(S): Mus musculus 
2021-11-01 | GSE182238 | GEO
GenomicsNoncoding SNPs decrease expression of FABP5 during COPD exacerbations
Noncoding SNPs decrease expression of FABP5 during COPD exacerbations
PRJNA1007645 | ENA
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