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TranscriptomicsTranscriptional profiling of 8Br-cAMP treated human H295R adrenal cortex
Transcriptional profiling of 8Br-cAMP exposed H295R cells at different time points (10h-24h-48h) and different concentrations (50uM-100uM-300uM) with untreated solvent control cells (blanks) Analysed on a H295R custom microarray, referred to as platform GPL9718 common reference design (pool of contr...
ORGANISM(S): Homo sapiens 
2011-11-15 | E-GEOD-32926 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse small intestine from PlagL2-/- animals reveals transcription factor PlagL2 regulates steps in chylomicron metabolism
Enterocytes assemble dietary lipids into chylomicron particles that are taken up by intestinal lacteal vessels and peripheral tissues. Although chylomicrons are known to assemble in part within membrane secretory pathways, the modifications required for efficient vascular uptake are unknown. We repo...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9123 | biostudies-arrayexpress
TranscriptomicsModulation of the transcriptional response to recombinant IFN-β by Acetaminophen
We examined the effect of acetaminophen (APAP) on the transcriptional response induced by interferon-β (IFN-β). Transcript levels from total RNA isolated rom murine livers were determined using G4121B whole genome arrays. Keywords: Pharmakinetics, drug treatment 6-8 week male CD-1 mice were admin...
ORGANISM(S): Mus musculus 
2010-10-18 | E-GEOD-18949 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and mutant fission yeast exposed to different intensities of H202 and two other oxidants
We studied transcriptional responses of the fission yeast Schizosaccharomyces pombe to different intensities of H2O2 stress as well as two other oxidants: menadione sodium bisulfite and tert-butyl hydroperoxide. DNA microarrays were used to study the changes in expression profiles and the transcrip...
ORGANISM(S): Schizosaccharomyces pombe 
2007-12-07 | E-MEXP-1083 | biostudies-arrayexpress
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