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MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
TranscriptomicsWinter and fall gene expression in rainbow smelt liver
Rainbow smelt (Osmerus mordax) are freeze-resistant fish that accumulate glycerol and produce an antifreeze protein during winter. Quantitative reverse transcription-PCR (qPCR) and subtractive hybridization studies have revealed a few genes in smelt liver to be differentially regulated in winter in...
ORGANISM(S): Osmerus mordax 
2010-05-15 | E-GEOD-17961 | biostudies-arrayexpress
TranscriptomicsGene expression in natural subyearling fall Chinook salmon in the Snake and Clearwater Rivers
We used gene expression accompanied by physical characteristics and gill Na+/K+-ATPase activity to analyze physiological differences associated with two life history variations of juvenile fall Chinook Salmon in the Snake River basin. Subyearlings originating in the Snake River typically migrate sea...
ORGANISM(S): Oncorhynchus tshawytscha 
2014-06-20 | E-GEOD-58670 | biostudies-arrayexpress
TranscriptomicsRobust inference of cell-to-cell expression variations from single- and k-cell profiling (RNA-Seq)
Quantifying heterogeneity in gene expression among single cells can reveal information inaccessible to cell-population measurements. However, the levels of many transcripts in single cells fall below the detection limit of even the most sensitive technologies currently available. One proposed approa...
ORGANISM(S): Homo sapiens 
2016-06-17 | GSE83450 | GEO
TranscriptomicsRobust inference of cell-to-cell expression variations from single- and k-cell profiling (10 cell RT-PCR)
Quantifying heterogeneity in gene expression among single cells can reveal information inaccessible to cell-population measurements. However, the levels of many transcripts in single cells fall below the detection limit of even the most sensitive technologies currently available. One proposed approa...
ORGANISM(S): Homo sapiens 
2016-06-17 | GSE83447 | GEO
TranscriptomicsRobust inference of cell-to-cell expression variations from single- and k-cell profiling (single cell RT-PCR)
Quantifying heterogeneity in gene expression among single cells can reveal information inaccessible to cell-population measurements. However, the levels of many transcripts in single cells fall below the detection limit of even the most sensitive technologies currently available. One proposed approa...
ORGANISM(S): Homo sapiens 
2016-06-17 | GSE83446 | GEO
TranscriptomicsGene expression in natural subyearling fall Chinook salmon in the Snake and Clearwater Rivers
We used gene expression accompanied by physical characteristics and gill Na+/K+-ATPase activity to analyze physiological differences associated with two life history variations of juvenile fall Chinook Salmon in the Snake River basin. Subyearlings originating in the Snake River typically migrate sea...
ORGANISM(S): Oncorhynchus tshawytscha Salmo salar 
2014-06-20 | GSE58670 | GEO
ProteomicsThe natural statin α,β-dehydromonacolin K exerts anti-secretory effect in human intestinal epithelial cells via a nonsense-mediated mRNA decay-dependent mechanism
The cAMP-induced intestinal chloride secretion plays a significant role in the pathogenesis of secretory diarrheas. This study aimed to investigate the anti-secretory effects of α,β-dehydromonacolin K, a derivative of lovastatin from Aspergillus sclerotiorum, on cAMP-induced chloride and fluid secre...
ORGANISM(S): Homo Sapiens (human) 
2025-01-01 | PXD058025 | JPOST Repository
UnknownRapid development of vasopressin resistance in dietary K+ deficiency.
Not available
S-EPMC8174811 | biostudies-literature
UnknownModeling and subtleties of K-Ras and Calmodulin interaction.
Not available
S-EPMC6226203 | biostudies-literature
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