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ProteomicsThe FAM83 family of proteins are anchors for Casein Kinase 1 isoforms through the DUF1669 domain
The Casein Kinase 1 (CK1) family of Ser/Thr protein kinases are implicated in the regulation of many cellular processes, including cell cycle, circadian rhythm, Wnt and Sonic Hedgehog signalling. Regarded as constitutively active kinases, their regulation in cells is critically important but poorly ...
ORGANISM(S): Homo sapiens (Human) 
2018-05-24 | PXD009335 | Pride
Fam83 proteomics 
ProteomicsFAM83F regulates canonical Wnt signalling through an interaction with CK1α
The function of the FAM83F protein, like the functions of many members of the FAM83 family, is poorly understood. Here we show that injection of Fam83f mRNA into Xenopus embryos causes axis duplication, a phenotype indicative of enhanced Wnt signalling. Consistent with this, overexpression of FAM83F...
ORGANISM(S): Homo sapiens (Human) 
2020-12-23 | PXD023121 | Pride
Fam83f 
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