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ProteomicsFAM83F regulates canonical Wnt signalling through an interaction with CK1α
The function of the FAM83F protein, like the functions of many members of the FAM83 family, is poorly understood. Here we show that injection of Fam83f mRNA into Xenopus embryos causes axis duplication, a phenotype indicative of enhanced Wnt signalling. Consistent with this, overexpression of FAM83F...
ORGANISM(S): Homo sapiens (Human) 
2020-12-23 | PXD023121 | Pride
Fam83f 
TranscriptomicsZebrafish reveal new roles for Fam83f in hatching and DNA damage-mediated autophagic responses
The FAM83 (Family with sequence similarity 83) family is highly conserved in vertebrates, yet little is known of the functions of these proteins beyond a correlation with oncogenesis. Of the family, FAM83F is of particular interest because it is the only membrane targeted FAM83 protein. FAM83F has b...
ORGANISM(S): Danio rerio 
2024-09-30 | GSE244291 | GEO
GenomicsZebrafish reveal new roles for Fam83f in hatching and DNA damage-mediated autophagic responses
Zebrafish reveal new roles for Fam83f in hatching and DNA damage-mediated autophagic responses
PRJNA1022096 | ENA
UnknownFam83F induces p53 stabilisation and promotes its activity.
Not available
S-EPMC6748130 | biostudies-literature
UnknownFAM83F regulates canonical Wnt signalling through an interaction with CK1α.
Not available
S-EPMC7768192 | biostudies-literature
UnknownIMiDs induce FAM83F degradation via an interaction with CK1α to attenuate Wnt signalling.
Not available
S-EPMC7768194 | biostudies-literature
UnknownUpregulation of FAM83F by c-Myc promotes cervical cancer growth and aerobic glycolysis via Wnt/β-catenin signaling activation.
Not available
S-EPMC10725447 | biostudies-literature
UnknownThe Highly Expressed FAM83F Protein in Papillary Thyroid Cancer Exerts a Pro-Oncogenic Role in Thyroid Follicular Cells.
Not available
S-EPMC6407429 | biostudies-literature
UnknownComprehensive analysis of the expression, prognostic significance, and function of FAM83 family members in breast cancer.
Not available
S-EPMC9158143 | biostudies-literature
UnknownWhole-Genome DNA Methylation Profiling Identifies Epigenetic Signatures of Uterine Carcinosarcoma.
Not available
S-EPMC5237802 | biostudies-literature
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