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ProteomicsStructure of the Fanconi anaemia monoubiquitin ligase complex
The Fanconi Anemia (FA) pathway repairs DNA damage caused by endogenous and chemotherapy-induced DNA crosslinks. Genetic inactivation of this pathway impairs development, prevents blood production and promotes cancer. The key molecular step in the FA pathway is the monoubiquitination of a heterodime...
ORGANISM(S): Gallus gallus (Chicken) 
2019-10-16 | PXD014282 | Pride
Fanconi anemia monoubiquitin ligase Human Crosslinking ms Em Electron microscopy Clms 
UnknownGenetic inactivation of FAAP100 causes Fanconi anemia due to disruption of the monoubiquitin ligase core complex.
Not available
S-EPMC12126235 | biostudies-literature
UnknownEffects of Sepantronium Bromide (YM-155) on the Whole Transcriptome of MDA-MB-231 Cells: Highlight on Impaired ATR/ATM Fanconi Anemia DNA Damage Response.
Not available
S-EPMC6070710 | biostudies-literature
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