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In vitro modeling of human disease has recently become feasible with the adoption of induced pluripotent stem cell (iPSC) technology. Here, we established patient-derived iPSCs from an Li-Fraumeni Syndrome (LFS) family and investigated the role of mutant p53 in the development of osteosarcoma (OS). ...
ORGANISM(S): Homo sapiens 
Gene expression profiling of wild-type and Li2 mutants were investigated with Affymetrix cotton Genome Array focused primarily on time-points related to fiber elongation, more specifically, 8 and 12 days post anthesis (DPA). These time points typically represent peak rates of elongation and the begi...
ORGANISM(S): Gossypium hirsutum 
Malassezia globosa is abundant and prevalent on sebaceous areas of the human skin. Genome annotation reveals that M. globosa possesses a repertoire of secreted hydrolytic enzymes relevant for lipid and protein metabolism on the skin. In-gel proteomics identifies a predicted aspartyl protease, MGL_33...
ORGANISM(S): Cellular Organisms 
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