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Comparions of transcriptomes of two osteocyte cell lines under conditions that increase and decrease androgens. To study gene expression differences and the cell lines' appropriateness for studying androgen regulation of skeletal function
ORGANISM(S): Mus musculus 
Chronic kidney disease (CKD) leads to bone loss and bone marrow adipose tissue (BMAT) accumulation. Sclerostin and dickkopf-1 (DKK1) are two inhibitors of Wnt signalling, which suppress bone formation, promote bone marrow adipogenesis, and are elevated in CKD. However, therapies targeting sclerostin...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD069117 | Pride
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