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MetabolomicsFASN effect on HCT116 metabolism probed by 13C6-glucose tracer (part II)
Not available
ORGANISM(S): Homo sapiens 
ST001046 | MetabolomicsWorkbench
MetabolomicsFASN effect on HCT116 metabolism probed by 13C6-glucose tracer (part I)
Not available
ORGANISM(S): Homo sapiens 
ST001045 | MetabolomicsWorkbench
TranscriptomicsMicroarray gene expression profiling of transgenic mice with myocardium-specific over-expression of fatty acid synthase (FASN)
The fatty acid synthase (FASN) is the major fat synthesizing enzyme. FASN is an indispensable enzyme because mice with genetic deletion of Fasn are not viable. Apart from its physiological function, previous studies indicated that FASN could also exert a pathophysiological role, in the heart, becaus...
ORGANISM(S): Mus musculus 
2013-07-31 | E-GEOD-49351 | biostudies-arrayexpress
ProteomicsFASN-dependent de novo lipogenesis is required for brain development
Fate and behaviour of neural progenitor cells is tightly regulated during mammalian brain development. Metabolic pathways, such as glycolysis and oxidative phosphorylation, that are required for supplying energy and providing molecular building blocks to generate cells, govern progenitor function. H...
ORGANISM(S): Homo sapiens (Human) 
2022-01-14 | PXD026110 | Pride
Fasn Human Mouse Lipogenesis Brain development Brain organoids 
ProteomicsThe Role of FASN in bladder cancer
To dissect the mechanistic interplay between fatty acid metabolism and cigarette smoke–induced signaling in bladder cancer, we employed a proteomics analysis xenograft tumors derived from the UMUC3 with either stable FASN knockdown (KD) or control shRNA, with and without cigarette smoke. We performe...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-06-15 | PXD068785 | Pride
Proteomics Fasn Cigarette smoke Bladder cancer 
ProteomicsThe deubiquitinase USP13 maintains cancer cell stemness by promoting FASN stability in small cell lung cancer
USP13 is significantly amplified in over 20% of lung cancer patients and critical for tumor progression. However, the functional role of USP13 in small cell lung cancer (SCLC) remains largely unclear. In this study, we found that the deubiquitinase USP13 is highly expressed in SCLC tumor samples and...
ORGANISM(S): Homo Sapiens 
PXD032993 |
TranscriptomicsGenome-wide analysis of fatty acid synthase (FASN) gene silenced normal liver cells (THLE 2) using cDNA microarray analysis
Fatty acid synthase is a major enzyme involved in de novo lipogenesis, associated with energy homeostasis, lipid storage and signalling in normal liver cells. The effect of fatty acid synthase knockdown in normal liver cells (THLE 2) using siRNA mediated gene silencing were assesed for global gene d...
ORGANISM(S): Homo sapiens 
2016-06-02 | E-GEOD-82096 | biostudies-arrayexpress
GenomicsRNA-Seq of chondrocyte with or without FASN knockdown
RNA-Seq of chondrocyte with or without FASN knockdown
PRJNA993404 | ENA
GenomicsFASN-Dependent NLRP3 Palmitoylation Drives Inflammasome Activation in Periodontitis [dataset1]
FASN-Dependent NLRP3 Palmitoylation Drives Inflammasome Activation in Periodontitis [dataset1]
PRJNA1314093 | ENA
GenomicsFASN-Dependent NLRP3 Palmitoylation Drives Inflammasome Activation in Periodontitis [dataset2]
FASN-Dependent NLRP3 Palmitoylation Drives Inflammasome Activation in Periodontitis [dataset2]
PRJNA1314098 | ENA
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