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MetabolomicsA next-generation yeast chassis: comprehensive characterization of a robust fast-growing Saccharomyces cerevisiae

Robust and efficient hosts are necessary to facilitate advances in biotechnology. We unveil Saccharomyces cerevisiae strain XP as a promising new microbial chassis owing to its high growth rate and robustness. This strain has a doubling time of 48.2 min, which is 12.8 min faster than the...

2024-09-26 | MTBLS7328 | MetaboLights
MetabolomicsMolecular mechanisms of growth differences in large yellow croaker: Metabolomic and metagenomic analyses

Gut microbiota can modulate nutrient metabolism, considerably affecting host growth and development. However, mechanisms by which gut microbiota regulate large yellow croaker (LYC; Larimichthys crocea) growth remain unclear. We assessed gut contents of fast-growing male (IWHM) and female (IWHF) L...

2024-08-02 | MTBLS10000 | MetaboLights
MetabolomicsAbsolute quantification of metabolites in tomato fruit extracts by fast 2D NMR (Tomato 700 MHz samples)

Quantitative NMR metabolomics is a powerful tool to have access to valuable information on metabolism. Unfortunately, the quantitative analysis of metabolic samples is often hampered by peak overlap. Two-dimensional (2D) spectroscopy offers a promising alternative and quantitative results can be ...

2015-11-11 | MTBLS132 | MetaboLights
MetabolomicsAbsolute quantification of metabolites in tomato fruit extracts by fast 2D NMR (Tomato 500 MHz samples)

Quantitative NMR metabolomics is a powerful tool to have access to valuable information on metabolism. Unfortunately, the quantitative analysis of metabolic samples is often hampered by peak overlap. Two-dimensional (2D) spectroscopy offers a promising alternative and quantitative results can be ...

2015-01-28 | MTBLS131 | MetaboLights
MetabolomicsAbsolute quantification of metabolites in tomato fruit extracts by fast 2D NMR (Calibration Standard 700 MHz samples)

Quantitative NMR metabolomics is a powerful tool to have access to valuable information on metabolism. Unfortunately, the quantitative analysis of metabolic samples is often hampered by peak overlap. Two-dimensional (2D) spectroscopy offers a promising alternative and quantitative results can be ...

2015-11-11 | MTBLS134 | MetaboLights
MetabolomicsAbsolute quantification of metabolites in tomato fruit extracts by fast 2D NMR (Calibration Standard 500 MHz samples)

Quantitative NMR metabolomics is a powerful tool to have access to valuable information on metabolism. Unfortunately, the quantitative analysis of metabolic samples is often hampered by peak overlap. Two-dimensional (2D) spectroscopy offers a promising alternative and quantitative results can be ...

2015-11-11 | MTBLS133 | MetaboLights
MetabolomicsGrowth control of the eukaryote cell: a systems biology study in yeast
Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each function...
2012-04-19 | MTBLS8 | MetaboLights
MetabolomicsMetaboFIMS: An automated workflow for fast and sensitive metabolic screening of large patient cohorts
Development of a fully untargeted FI-MS processing pipeline.
2026-04-24 | MTBLS14362 | MetaboLights
TranscriptomicsExercise promotes growth and vascularization of fast skeletal muscle by activating myogenic and angiogenic transcriptional programs in adult zebrafish
The adult skeletal muscle is a plastic tissue with a remarkable ability to adapt to different levels of activity by altering its excitability, its contractile and metabolic phenotype and its mass. Knowledge on the mechanisms responsible for muscle mass comes primarily from models of muscle inactivit...
ORGANISM(S): Danio rerio 
2014-12-23 | E-GEOD-58929 | biostudies-arrayexpress
MetabolomicsDynamic utilization of low-molecular-weight organic substrates across a microbial growth rate gradient

AIM: Low-molecular-weight organic substances (LMWOSs) are at the nexus between micro-organisms, plant roots, detritus and the soil mineral matrix. The nominal oxidation state of carbon (NOSC) has been suggested as a potential parameter for modelling microbial uptake rates of LMWO...

2023-08-14 | MTBLS3558 | MetaboLights
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