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ProteomicsIdentification of vitamin K-dependent proteins in mouse liver by LC-MS/MS
Vitamin K (VK), a fat-soluble vitamin, functions as a co-factor during the gamma-carboxylation reaction that converts glutamic acid residues to gamma-carboxyglutamic acid residues in proteins transiting through the endoplasmic reticulum. Two enzymes are involved which together form the VK cycle: gam...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD032920 | Pride
Gamma-carboxylation Mouse Liver Vitamin k Lc-ms/ms 
ProteomicsIgSF21-interacting protein screen
We have recently isolated IgSF21 (IGIS) as a novel synaptic organizer that selectively promotes inhibitory presynaptic differentiation. To isolate IgSF21 receptor that mediates synapse-promoting activity of IgSF21, we performed proteomics-based screen using cultured hippocampal neurons with IgSF21-c...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-09-04 | PXD006622 | Pride
Synaptic adhesion molecules Hippocampal neurons Lc-ms/ms 
ProteomicsDNA binding reorganizes the intrinsically disordered C-terminal region of PSC in Drosophila PRC1
Polycomb Group (PcG) proteins regulate gene expression by modifying chromatin. A key PcG complex, PRC1, has two activities: a ubiquitin ligase activity for histone H2A, and a chromatin compacting/nucleosome bridging activity that can inhibit transcription and chromatin remodeling. In Drosophila, the...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2020-05-15 | MSV000085418 | MassIVE
MetabolomicsA Metabolic Profiling Strategy for the Dissection of Plant Defense against Fungal Pathogens (GC-MS assay)
Here we present a metabolic profiling strategy employing direct infusion Orbitrap mass spectrometry (MS) and gas chromatography-mass spectrometry (GC/MS) for the monitoring of soybean's (Glycine max L.) global metabolism regulation in response to Rhizoctonia solani infection in a time-course. Key el...
2014-11-15 | MTBLS118 | MetaboLights
MetabolomicsA Metabolic Profiling Strategy for the Dissection of Plant Defense against Fungal Pathogens (DI-MS assays)
Here we present a metabolic profiling strategy employing direct infusion Orbitrap mass spectrometry (MS) and gas chromatography-mass spectrometry (GC/MS) for the monitoring of soybean's (Glycine max L.) global metabolism regulation in response to Rhizoctonia solani infection in a time-course. Key el...
2014-11-15 | MTBLS117 | MetaboLights
ProteomicsAfrican swine fever virus proteins MGF360-21R and A151R interact with barrier-to-autointegration factor 1 (BANF1)
African swine fever virus (ASFV) is a large DNA virus causing a highly contagious disease in domestic and wild boar, for which no treatment is available. ASFV vaccine development is hindered by large gaps in knowledge considering virus protein function and virus-host interaction. This study identifi...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2025-07-23 | PXD047794 | Pride
Mgf360-21r A151r Asfv Banf1 Virus-host ppi 
MetabolomicsMetaboLights MTBLS117 - GNPS A Metabolic Profiling Strategy for the Dissection of Plant Defense against Fungal Pathogens (DI-MS assays)
This data set is downloaded from MetaboLights (http://www.ebi.ac.uk/metabolights/) accession number MTBLS117 Abstract:Here we present a metabolic profiling strategy employing direct infusion Orbitrap mass spectrometry (MS) and gas chromatography-mass spectrometry (GC/MS) for the monitoring of soybea...
ORGANISM(S): Glycine Max/ncbitaxon:rhizoctonia Solani 
2017-04-12 | MSV000080916 | GNPS
MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
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