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ProteomicsIdentify the interacting proteins of FBXL4 by AP-MS
Affinity purification coupled with mass spectrometry (AP-MS) is powerful tools to define the interactome for a specific protein bait. Whereas AP-MS results in the identification of proteins that are in a stable complex.Mass spectrometry was performed to identify the interacting proteins of FBXL4 fro...
ORGANISM(S): Homo sapiens (Human) 
2024-05-12 | PXD040601 | Pride
Human Fbxl4 Ap-ms 
ProteomicsAnalysis of proteomic changes in Fbxl4 knock-out mouse liver and patient fibroblasts
We analyzed the proteomic changes that occur in a Fbxl4 knock-out 1-year mouse. We analyzed Liver tissue using a 6-plex TMT approach (3 KO and 3 controls). Since we observed a global decrease in mitochondrial proteins, we also explored mitoproteome changes in different tissues (liver, kidney and hea...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-06-10 | PXD018639 | Pride
Mitochondria Human Mouse Fibroblast Fbxl4 Liver 
UnknownFBXL4 deficiency increases mitochondrial removal by autophagy.
Not available
S-EPMC7338799 | biostudies-literature
UnknownIdentification of FBXL4 as a Metastasis Associated Gene in Prostate Cancer.
Not available
S-EPMC5505985 | biostudies-literature
Genomics
Functional study of variants in FBXL4
PRJNA590845 | ENA
UnknownDichloroacetate improves mitochondrial function, physiology, and morphology in FBXL4 disease models.
Not available
S-EPMC9462489 | biostudies-literature
UnknownMutations in FBXL4, encoding a mitochondrial protein, cause early-onset mitochondrial encephalomyopathy.
Not available
S-EPMC3769923 | biostudies-literature
Genomics
Functional study of variants in the FBXL4 gene
PRJNA592374 | ENA
UnknownMolecular Characterization of New FBXL4 Mutations in Patients With mtDNA Depletion Syndrome.
Not available
S-EPMC6960396 | biostudies-literature
UnknownHyperammonemia as a Presenting Feature in Two Siblings with FBXL4 Variants.
Not available
S-EPMC5585110 | biostudies-literature
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