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Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic strategy for Inflammatory Bowel Disease (UC), though its clinical success appears contingent upon donor microbiota engraftment degree. While microbial colonization dynamics remain poorly understood, our study identifies...

2026-01-11 | MTBLS12531 | MetaboLights
The imbalance of intestinal flora can affect the immune function and structural integrity of the intestinal barrier, leading to the colonization and reproduction of opportunistic pathogenic bacteria in the intestine to become the dominant flora, eventually inducing enteritis. This study aimed to inv...
2024-03-26 | MTBLS9451 | MetaboLights

Extract the intestinal contents of Trachemys scripta elegans subjected to environmental stress at a salinity of ten PSU for 6 months, isolate the gut microbiota, and transplant them into other healthy Trachemys scripta elegans to observe their gut microbiota metabolite. Add GAGA and Arg to the fe...

2025-07-09 | MTBLS12187 | MetaboLights

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
The gut microbiota is the largest and most complex microecosystem in animals. It is influenced by the host's dietary habits and living environment, and its composition and diversity play irreplaceable roles in animal nutrient metabolism, immunity, and adaptation to the environment. Although the gut ...
2024-08-08 | MTBLS6121 | MetaboLights
This study aimed to analyze changes in gut microbiota composition in mice after transplantation of fecal microbiota (FMT, N = 6) from the feces of NSCLC patients by analyzing fecal content using 16S rRNA sequencing, 10 days after transplantation. Specific-pathogen-free (SPF) mice were used for each ...
ORGANISM(S): Mus musculus 

Age-related cataract (ARC) is a leading cause of vision loss whose underlying mechanisms remain incompletely understood. Emerging evidence suggests the gut microbiota can influence ocular health via systemic metabolic and inflammatory pathways, yet the gut–eye connection in cataract has not been ...

2025-09-03 | MTBLS12932 | MetaboLights

Radiation-induced lung injury (RILI) is a severe side effect of radiation therapy, characterized by lung tissue damage, inflammation, and organ dysfunction. Although fecal microbiota transplantation (FMT) has shown potential in alleviating radiation-induced damage, its underlying mechanisms ...

2026-01-05 | MTBLS12699 | MetaboLights
Abstract Objective: Functional constipation (FC) is a common gastrointestinal disorder that significantly affects quality of life. Increasing evidence suggests that gut microbiota and their derived metabolites play a critical role in FC, yet the therapeutic potential of Spirulina and its underlying ...
2026-09-30 | MTBLS15871 | MetaboLights
Inappropriate cross talk between mammals and their gut microbiota may trigger intestinal inflammation and drive extra-intestinal immune-mediated diseases. Studies with germ-free or gnotobiotic animals represent the gold standard for research on bacterial-host interaction but they are not readily acc...
ORGANISM(S): Mus musculus 
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