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ProteomicsTandem Mass Tag-Based Quantitative Proteomic Profiling Identifies Novel Serum Biomarkers of Drug-Induced Liver Injury in Humans
Diagnosis of drug-induced liver injury (DILI) and its distinction from other liver diseases are significant challenges in drug development and clinical practice. In this study we identify, confirm, and replicate the biomarker performance characteristics of candidate proteins in a cohort of patients ...
ORGANISM(S): Homo Sapiens 
2024-01-04 | PXD034882 | panorama
ProteomicsThe axonal sorting activity of pseudorabies virus Us9 protein depends on the state of neuronal maturation The axonal sorting activity of pseudorabies virus Us9 protein depends on the state of neuronal maturation
Alpha-herpesviruses establish a life-long infection in the nervous system of the affected host; while this infection is restricted to peripheral neurons in a heathy host, it can spread within the neuronal circuitry in compromised individuals leading to adverse health consequences. Pseudorabies viru...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-01-04 | PXD017822 | Pride
Virus-host Tmt Ip-ms Lfq Us9 Prv Dda 
UnknownEffect of Season of Birth on Hippocampus Volume in a Transdiagnostic Sample of Patients With Depression and Schizophrenia.
Not available
S-EPMC9234120 | biostudies-literature
UnknownQuadricuspid aortic valve repair: Results of a phenotype-based approach.
Not available
S-EPMC11998587 | biostudies-literature
ProteomicsTargeted MS assay to evaluate Cereblon neosubstrate changes in rabbit embryos following maternal administration of IMiDs
Targeted protein degradation is the selective removal of a protein of interest through hijacking intracellular protein cleanup machinery. This rapidly growing field currently relies heavily on the use of the E3 ligase Cereblon (CRBN) to target proteins for degradation, including the immunomodulatory...
ORGANISM(S): Oryctolagus Cuniculus 
PXD050568 | panorama
UnknownIncreased functional connectivity of amygdalar-frontal pathways in patients with alcohol use disorder and childhood trauma.
Not available
S-EPMC12172749 | biostudies-literature
ProteomicsOrganelle remodeling across infection time: Cytomegalovirus-host protein interactions viewed through the lens of Inter-ViSTA
Nearly all biological processes rely on the finely-tuned coordination of protein interactions across cellular space and time. Accordingly, generating protein interactome datasets has become routine in biological studies, yet effectively interpreting these datasets remains computationally challenging...
ORGANISM(S): Homo sapiens (Human) 
2020-08-03 | PXD017163 | Pride
Ap-ms Ul37 Hcmv Pul37x1 Ppi 
UnknownReduced structural connectivity of the amygdala is associated with childhood trauma in adult patients with alcohol use disorder.
Not available
S-EPMC9286842 | biostudies-literature
UnknownFunctional connectivity and upper limb function in patients after pediatric arterial ischemic stroke with contralateral corticospinal tract wiring.
Not available
S-EPMC7943570 | biostudies-literature
UnknownSMAD3 contributes to ascending aortic dilatation independent of transforming growth factor-beta in bicuspid and unicuspid aortic valve disease
Not available
S-EPMC9474869 | biostudies-literature
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