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TranscriptomicsLamin A/C Is Required For ChAT-Dependent Neuroblastoma Differentiation: a microarray gene expression study
The mouse neuroblastoma N18TG2 clone is unable to differentiate and defective for the enzymes of the biosynthesis of neurotransmitters. The forced expression of choline acetyltransferase (ChAT) in these cells results in the synthesis and release of acetylcholine (Ach) and hence in the expression of ...
ORGANISM(S): Mus musculus 
2017-04-18 | E-GEOD-73591 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of the AD11 anti-NGF transgenic mouse model of neurodegeneration at 1, 3, 6, 15 months of age
We characterized the gene expression profile of brain regions at different stages of the AlzheimerM-bM-^@M-^Ys like neurodegeneration in the anti-NGF AD11 trangenic mouse model. Total RNA was extracted from hippocampus, cortex and basal forebrain of postnatal day 30 (P30, 1 month), P90 (3 months), P...
ORGANISM(S): Mus musculus 
2015-02-26 | E-GEOD-63617 | biostudies-arrayexpress
TranscriptomicsLamin A/C is required for SHSY5Y neuroblastoma cell differentiation and its expression is linked to a less malignant phenotype.
The main scientific objective of the project was to investigate whether Lamin A/C could be involved in neuroblastoma differentiation. Moreover, taking into account the significance of differentiation stage in the neuroblastoma tumor progression we have also studied a possible role of Lamin A/C in th...
ORGANISM(S): Homo sapiens 
2013-07-11 | E-GEOD-30677 | biostudies-arrayexpress
UnknownExome sequencing of glioblastoma-derived cancer stem cells reveals rare clinically relevant frameshift deletion in MLLT1 gene.
Not available
S-EPMC8740446 | biostudies-literature
UnknownThe transcriptome and miRNome profiling of glioblastoma tissues and peritumoral regions highlights molecular pathways shared by tumors and surrounding areas and reveals differences between short-term and long-term survivors.
Not available
S-EPMC4673180 | biostudies-literature
UnknownSignaling by exosomal microRNAs in cancer.
Not available
S-EPMC4391656 | biostudies-literature
UnknownCirculating miRNAs in Small Extracellular Vesicles Secreted by a Human Melanoma Xenograft in Mouse Brains.
Not available
S-EPMC7352810 | biostudies-literature
TranscriptomicsDeep-sequencing of endogenous microRNAs from human endothelial cells exposed to hypoxia and normoxia
Human Umbelical Vein Endothelial Cells (HUVEC) were cultured in vitro and exposed to 1% oxygen or normoxia for 24 hours. Then, small RNA libraries were prepared and sequenced using sequencing-by-ligation technique (Solid3 Plus Sequencer platform). Alignment versus miRBase v14.0 identified >400 diffe...
ORGANISM(S): Homo sapiens 
2012-02-07 | E-GEOD-26497 | biostudies-arrayexpress
UnknownMYC prevents apoptosis and enhances endoreduplication induced by paclitaxel.
Not available
S-EPMC2673584 | biostudies-literature
UnknownMYCN gene expression is required for the onset of the differentiation programme in neuroblastoma cells.
Not available
S-EPMC3944258 | biostudies-literature
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