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ProteomicsProteomic Profiling of Inflammatory versus Noninflammatory Cartilage Regions in Knee Osteoarthritis Patients
This study performed data-independent acquisition (DIA)-based quantitative proteomic analysis on paired cartilage samples from inflammatory and noninflammatory regions of knee osteoarthritis (OA) patients. The objective was to characterize the proteomic alterations associated with cartilage inflamma...
ORGANISM(S): Homo Sapiens 
2026-05-19 | PXD078593 |
ProteomicsBCAT1 Confers Resistance to EGFR TKIs through α-KG-dependent Epigenetic Regulation of the Glycolysis Pathway in NSCLC
Epidermal growth factor receptor (EGFR) mutations are leading oncogenic drivers in non-small cell lung cancer (NSCLC). Many third-generation EGFR tyrosine kinase inhibitors (TKIs) have been developed to target EGFR T790M and activating mutations. Osimertinib (AZD9291) was the first approved drug and...
ORGANISM(S): Homo Sapiens 
2023-07-14 | PXD043776 |
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