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UnknownThe novel compound heterozygous variants identified in a Chinese family with glucose phosphate isomerase deficiency and pathogenicity analysis.
Not available
S-EPMC10332073 | biostudies-literature
ProteomicsThe proteomics data for Increased matrix stiffness promotes fibrogenesis of hepatic stellate cells through AP-1-induced chromatin priming
Matrix stiffness has significant effects on cell behavior, however, less is known regarding the epigenomic and transcriptional regulation underling the effect of matrix stiffness on cells. In this study, we use an in vitro system to assess the phenotypic shifts of hepatic stellate cells (HSCs) follo...
ORGANISM(S): Homo Sapiens 
2025-04-19 | PXD063173 |
ProteomicsBiomarkers in Plasma Exosomes Reveal Molecular Pathways of Postoperative Delirium: New Horizons from Diagnosis to Treatment
Background: Delirium diagnosis currently lacks objective biomarkers and is based solely on clinical observation, with incomplete understanding of underlying mechanisms. This study aims to explore the proteomic and metabolomic profiles of exosomes for postoperative delirium (POD) diagnosis and to und...
ORGANISM(S): Homo Sapiens 
2024-03-27 | PXD051005 |
ProteomicsProteomics reveals the ribosome signaling pathway promoting prostate cancer progression and correlating with poor prognosis
Through digital rectal examinations and routine prostate-specific antigen (PSA) screening, early treatment of prostate cancer has become possible. However, prostate cancer is a complex and heterogeneous disease. In many patients, cancer cells can invade adjacent tissues and metastasize to other tiss...
ORGANISM(S): Homo Sapiens 
2021-09-05 | PXD028211 |
ProteomicsDIA-Based Quantitative Proteomic Analysis of HAEC cells
We explored the protective mechanisms of phytochemicals against palmitate induced lipotoxicity using data independent acquisition-based quantitative proteomic. Among the differently expressed proteins in response to palmitate liptoxicity, 93 of them were reversed after apigenin administration and th...
ORGANISM(S): Homo Sapiens 
2020-07-17 | PXD020424 |
ProteomicsRipening stage-resolved proteome and phosphoproteome profiling of tomato fruits reveals the involvement of reduced chloroplast coverage protein REC1a in fruit ripening
Fruit ripening in tomato (Solanum lycopersicum) has been extensively studied at the molecular, biochemical, physiological, and transcriptomic levels, but comprehensive profiling of tomato fruit proteome and phosphoproteome remain limited. Plastid development and differentiation are critical for toma...
ORGANISM(S): Solanum Lycopersicum 
2024-04-19 | PXD051570 |
ProteomicsChaperonin TRiC bridges radial spokes for folding proteins locally translated in mammalian sperm flagella
As animals evolved from external to internal fertilization, sperm flagella, which once transiently propelled sperm in water to reach nearby eggs, developed to beat for days or even longer within the female reproductive tract. How flagella were remodeled accordingly remains unclear. Unlike externally...
ORGANISM(S): Bos Taurus 
2025-08-12 | PXD067693 |
ProteomicsThe pan-cancer lncRNA PLANE regulates an alternative splicing program and promotes cancer pathogenesis
Proteome analysis of Biotin- PLANE pull-down assays
ORGANISM(S): Homo Sapiens 
2020-11-26 | PXD022747 |
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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