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GenomicsComparative analysis of the Illumina Mouse Methylation BeadChip and Reduced Representation Bisulphite Sequencing for routine DNA methylation analysis of murine samples
Background: Researching the murine epigenome in disease models has been hampered by the lack of an appropriate and cost-effective DNA methylation array. Until recently, investigators have been limited to the relatively expensive and analysis intensive bisulphite sequencing methods. Here, we performe...
ORGANISM(S): Mus musculus 
2022-10-15 | E-MTAB-12214 | biostudies-arrayexpress
TranscriptomicsGenome-Scale interrogation of the colorectal cancer methylome by Illumina HumanMethylation450 array
Colorectal cancer is an epigenetically heterogeneous disease, the extent to which is unclear. In this study we interrogate the methylome of 216 unselected colorectal cancers using Illumina HumanMethylation450 arrays, and correlate these data with transcript profiles and exome sequencing analysis to ...
ORGANISM(S): Homo sapiens 
2019-04-29 | E-MTAB-7036 | biostudies-arrayexpress
TranscriptomicsComparative analysis of the Illumina Mouse Methylation BeadChip and Reduced Representation Bisulphite Sequencing for routine DNA methylation analysis of murine samples
Background: Researching the murine epigenome in disease models has been hampered by the lack of an appropriate and cost-effective DNA methylation array. Until recently, investigators have been limited to the relatively expensive and analysis intensive bisulphite sequencing methods. Here, we performe...
ORGANISM(S): Mus musculus 
2022-08-31 | E-MTAB-11985 | biostudies-arrayexpress
TranscriptomicsGenome-Scale interrogation of the colorectal cancer methylome and transcriptome by microarray
Colorectal cancer is an epigenetically heterogeneous disease, the extent to which is unclear. In this study we interrogate the methylome of 216 unselected colorectal cancers using Illumina HumanMethylation450 arrays, and correlate these data with transcript profiles and exome sequencing analysis to ...
ORGANISM(S): Homo sapiens 
2019-07-17 | E-MTAB-8148 | biostudies-arrayexpress
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