Sort   by:  
 Page size 
UnknownSynthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents.
A library of structurally related coumarins was generated through synthesis reactions and chemical modification reactions to obtain derivatives with antiproliferative activity both in vivo and in vitro. Out of a total of 35 structurally related coumarin derivatives, seven of them showe...
S-EPMC10373209 | biostudies-literature
UnknownHolmes tremor: Clinical description, lesion localization, and treatment in a series of 29 cases.

Objective

To describe the clinical features, etiology, findings from neuroimaging, and treatment results in a series of 29 patients with Holmes tremor (HT).

Methods

A retrospective study was performed based on review of medical records and videos of patients with HT diagnosis.

Resu...

S-EPMC4782118 | biostudies-literature
UnknownInhibition of bacterial quorum sensing by extracts from aquatic fungi: first report from marine endophytes.
In our search for quorum-sensing (QS) disrupting molecules, 75 fungal isolates were recovered from reef organisms (endophytes), saline lakes and mangrove rhizosphere. Their QS inhibitory activity was evaluated in Chromobacterium violaceum CVO26. Four strains of endophytic fungi stood out for their p...
S-EPMC4245542 | biostudies-literature
UnknownDiagnostic accuracy cohort study and clinical value of the Histoplasma urine antigen (ALPHA Histoplasma EIA) for disseminated histoplasmosis among HIV infected patients: A multicenter study.

Background

The Histoplasma urine antigen (HUAg) is the preferred method to diagnose progressive disseminated histoplasmosis (PDH) in HIV patients. In 2007, IMMY ALPHA Histoplasma EIA was approved for clinical for on-site use, and therefore useful for regions outside the United States. Howeve...
S-EPMC6237426 | biostudies-literature
UnknownNationwide genetic analysis of more than 600 families with inherited eye diseases in Argentina.
This study corresponds to the first large-scale genetic analysis of inherited eye diseases (IED) in Argentina and describes the comprehensive genetic profile of a large cohort of patients. Medical records of 22 ophthalmology and genetics services throughout 13 Argentinian provinces were analyzed ret...
S-EPMC10202926 | biostudies-literature
UnknownDiagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico.

Background

The progressive disseminated histoplasmosis (PDH) has been associated with severe disease and high risk of death among people living with HIV (PLWHIV). Therefore, the purpose of this multicenter, prospective, double-blinded study done in ten Mexican hospitals was to determine the ...
S-EPMC7971897 | biostudies-literature
UnknownSARS-CoV-2 infection in patients with melanoma: results of the Spanish Melanoma Group registry.

Background

The Spanish Melanoma Group (GEM) developed a national registry of patients with melanoma infected by SARS-CoV-2 ("GRAVID").

Methods

The main objective was to describe the COVID-19 fatality rate in patients with melanoma throughout the pandemic, as well as to explore the eff...
S-EPMC9789885 | biostudies-literature
UnknownSociodemographic and clinical factors associated with poor COVID-19 outcomes in patients with rheumatic diseases: data from the SAR-COVID Registry.

Background/objective

This study aims to describe the course and to identify poor prognostic factors of SARS-CoV-2 infection in patients with rheumatic diseases.

Methods

Patients ≥ 18 years of age, with a rheumatic disease, who had confirmed SARS-CoV-2 infection were consecutively incl...
S-EPMC9535223 | biostudies-literature
UnknownSex differences in the diagnosis latency of Parkinson's disease in Latin America.

Background

Age and sex are known risk factors for Parkinson's Disease (PD), but it remains controversial if there are sex differences in the diagnosis latency. The objective of this study was to examine these sex differences in Latin America.

Methods

The Latin American Research Consor...
S-EPMC12703624 | biostudies-literature
UnknownCorticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study.

Purpose

To determine clinical predictors associated with corticosteroid administration and its association with ICU mortality in critically ill patients with severe influenza pneumonia.

Methods

Secondary analysis of a prospective cohort study of critically ill patients with confirmed ...
S-EPMC7095489 | biostudies-literature
Sort   by:  
 Page size