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The objective of the study was to identify the fertility-associated metabolites in bovine spermatozoa using liquid chromatography-mass spectrometry (LC-MS). Six Holstein Friesian crossbred bulls (three high-fertile and three low-fertile bulls) were the experimental animals. Sperm proteins were isola...
2021-12-07 | MTBLS1071 | MetaboLights
Bull fertility impacts herd fertility, but accurately predicting male fertility from sperm characteristics is difficult once extremes are removed. The objectives of this study are identification, relative quantification, and comparison of sperm head plasma membrane (HPM) proteomics in bulls of diffe...
ORGANISM(S): Bos taurus (Bovine) 
2026-06-08 | PXD047294 | Pride
The development of biomarkers of fertility could provide benefits for the genetic improvement of dairy cows. Circulating small extracellular vesicles (sEVs) show promise as diagnostic or prognostic markers since their cargo reflects the metabolic state of the cell of origin; thus, they mirror the ph...
ORGANISM(S): Bos taurus (Bovine) 
2023-10-14 | PXD042891 | Pride
Predicting male fertility remains a major challenge in livestock industry. Seminal plasma contains a heterogeneous population of extracellular vesicles (sEVs) that are involved in the regulation of sperm functionality and may therefore be involved in male fertility. The aim of this study was to eval...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-02-02 | PXD055970 | Pride
Pregnancy rates for elite bulls used in artificial insemination (AI) can vary significantly and therefore the identification of molecular markers for bull fertility and targets to improve bull selection is important. β-defensins are peptides with diverse regulatory roles in sperm function across mul...
ORGANISM(S): Bos taurus 
The molecular basis of male infertility is still not well understood. Furthermore, in vitro sperm quality tests are poorly correlated to in vivo fertility. In order to better understand sperm biology and determine potential fertility biomarkers, we used a quantitative bottom-up proteomic approach to...
ORGANISM(S): Gallus gallus (Chicken) 
2021-08-17 | PXD022322 | Pride
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