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ProteomicsTraffic jam directly regulates the Drosophila piRNA cluster flamenco and the Piwi pathway gene network to ensure transposon silencing and female fertility.
The flamenco (flam) locus is the most prominent piRNA cluster locus expressed in Drosophila ovarian follicle cells that is required for female fertility and silencing of gypsy/mdg4 transposons. Although P-element insertions in the flam promoter region disrupts flam piRNAs and cause female infertilit...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-04-01 | PXD052946 | Pride
Transcription Tmt Multiplexed proteomics Traffic jam Affinity enrichment Transposon Pirna Fertilitym transposon Drosophila melanogaster 
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