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GenomicsIntegrative and comparative genomics identifies the tyrosine kinase FES as a key melanoma tumor supppressor: WGS
An incomplete view of the (epi)genetic events that drive melanoma initiation and progression has been a major barrier to rational development of effective therapeutics and prognostic diagnostics for melanoma patients. Recent approaches that integrate human melanoma genomic and transcriptomic data pr...
ORGANISM(S): Mus musculus 
2017-05-03 | E-MTAB-4921 | biostudies-arrayexpress
GenomicsIntegrative and comparative genomics identifies the tyrosine kinase FES as a key melanoma tumor supppressor: WES
An incomplete view of the (epi)genetic events that drive melanoma initiation and progression has been a major barrier to rational development of effective therapeutics and prognostic diagnostics for melanoma patients. Recent approaches that integrate human melanoma genomic and transcriptomic data pr...
ORGANISM(S): Mus musculus 
2017-05-03 | E-MTAB-4917 | biostudies-arrayexpress
GenomicsIntegrative and comparative genomics identifies the tyrosine kinase FES as a key melanoma tumor supppressor: WGS part 2
An incomplete view of the (epi)genetic events that drive melanoma initiation and progression has been a major barrier to rational development of effective therapeutics and prognostic diagnostics for melanoma patients. Recent approaches that integrate human melanoma genomic and transcriptomic data pr...
ORGANISM(S): Mus musculus 
2017-05-03 | E-MTAB-5590 | biostudies-arrayexpress
TranscriptomicsSkeletal Muscle Contraction Reduces Effects of Unloading on Bone Independently from the Central Nervous System: Studies Using Functional Electrical Stimulation after Spinal Cord Transection
Spinal cord injury (SCI) causes severe bone loss and disrupts connections between higher centers in the central nervous system (CNS) and bone. Muscle contraction elicited by functional electrical stimulation (FES) partially protects against loss of bone but cellular and molecular events by which th...
ORGANISM(S): Rattus norvegicus 
2012-06-27 | E-GEOD-30301 | biostudies-arrayexpress
Genomicssludge sample in a coulped system (Anammox and FeS-driven denitrification)
sludge sample in a coulped system (Anammox and FeS-driven denitrification) Raw sequence reads
PRJNA917812 | ENA
ProteomicsOverlapping binding site for ferredoxin and frataxin on yeast cysteine desulfurase participating in FeS cluster biogenesis
In mitochondria cysteine desulfurase (Nfs1) plays a central role in the biosynthesis of iron-sulfur (FeS) clusters, cofactors critical for activity of many cellular proteins. Nfs1 functions both as a sulfur donor for cluster assembly and as a binding platform for other proteins functioning in the pr...
ORGANISM(S): Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2022-04-04 | PXD029519 | Pride
Lc-msms Protein complex Iron-sulfur protein 
TranscriptomicsFes-Deficient Macrophages Prime CD8+ T Cells to Stimulate Anti-tumor Immunity and Improve Immunotherapy Efficacy
Homeostatic immunoregulatory mechanisms that prevent adverse effects of immune overaction can serve as barriers to successful anti-cancer immunity, representing attractive targets to improve cancer immunotherapy. Here, we demonstrated the role of the non-receptor tyrosine kinase Fes, abundantly expr...
ORGANISM(S): Mus musculus 
2025-04-28 | GSE295079 | GEO
GenomicsFes-Deficient Macrophages Prime CD8+ T Cells to Stimulate Anti-tumor Immunity and Improve Immunotherapy Efficacy
Fes-Deficient Macrophages Prime CD8+ T Cells to Stimulate Anti-tumor Immunity and Improve Immunotherapy Efficacy
PRJNA1252769 | ENA
TranscriptomicsRNA-sequencing of Fes KO and WT melanomas
Publication abstract: An incomplete view of the (epi)genetic events that drive melanoma initiation and progression has been a major barrier to rational development of effective therapeutics and prognostic diagnostics for melanoma patients. Recent approaches that integrate human melanoma genomic and ...
ORGANISM(S): Mus musculus 
2017-06-21 | GSE83580 | GEO
UnknownReverse micelle-mediated synthesis of precision-controlled FeS nanospheres and their role in tailored FeS@PANI nanocomposites.
Not available
S-EPMC12558042 | biostudies-literature
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