Fielden J J - OmicsDI

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CRUK and MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK (1)
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Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne 3000, Australia (1)
Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia (1)
Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia. (1)
Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK (1)
Target Discovery Institute, University of Oxford, UK (1)

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Non-genotoxic Hepatocarcinogens

There is no accurate and well-validated short-term test for non-genotoxic carcinogens, necessitating an expensive two year rodent bioassay before a risk assessment can begin. We have developed a short-term in vivo rat assay that predicts whether non-genotoxic chemicals are likely to induce hepatic t...

ORGANISM(S): Rattus norvegicus

2007-06-22 | E-GEOD-8251 | biostudies-arrayexpress

Liver Pharmacology and Xenobiotic Response Repertoire

A definition of RNA expression changes that correlate with liver response programs and an understanding of the similarities and differences in responses to different classes of chemicals would aid in new chemical or drug characterization and add to our understanding of liver biology. We have used a ...

ORGANISM(S): Rattus norvegicus

2008-03-28 | E-GEOD-8858 | biostudies-arrayexpress

Expression data from rat urinary bladder and non-glandular stomach tissue samples

Seven novel and potent Raf small molecule kinase inhibitors were evaluated in 7-day oral repeat-dose rat toxicity studies. All compounds tested induced hyperplasia in multiple tissues. Microarrays were used to investigate transciptional changes associated by treatment with a single compound to gain ...

ORGANISM(S): Rattus norvegicus

2011-07-18 | E-GEOD-26936 | biostudies-arrayexpress

TEX264 at the intersection of autophagy and DNA repair.

Not available

S-EPMC8865260 | biostudies-literature

Quantitative mitochondrial proteome analysis during MceC expression time-course

Mitochondria were isolated from tetracycline-inducible control (EV) HEK293 cells or HEK293 cells expressing the C. burnetii effector protein MceC for 1, 4 and 8 hours.

ORGANISM(S): Homo sapiens (Human) Coxiella burnetii RSA 493

2020-11-12 | PXD021704 | Pride