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TranscriptomicsNP-18 vs. NP-18AR transcriptional profile upon treatment with TK/GCV
Pancreatic cancer-derived cells NP-18 underwent four rounds of treatment with increasing doses of an adenoviral vector encoding TK enzyme and GCV. Surviving cells were termed NP-18AR and displayed decreased sensitivity to treatment. This experiment analyses the transcriptomic effect of TK/GCV treatm...
ORGANISM(S): Homo sapiens 
2010-07-16 | E-GEOD-17137 | biostudies-arrayexpress
ProteomicsExoproteome of a furC-overexpressing strain: FurC tunes peptidoglycan remodeling and intercell transfer
To study the effect of FurC overexpression in the exoproteome composition of Anabaena, sp. PCC120, SWATH-MS analyses have been carried out with the isolated exoproteome of the FurC overexpressing strain, EB2770FurC (named in the present dataset "EB") comparing to the one of the wild-type strain (WT)...
ORGANISM(S): Nostoc sp. (strain PCC 7120 / UTEX 2576) 
2024-02-07 | PXD043659 | Pride
Furc Swath Peptidoglycan Perr Transfer 
TranscriptomicsRNA-seq of Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120) wild-type strain compared to a FurC-overexpressing derivative strain grown in BG11 and after 48 hours of nitrogen-step down.
Here, we report the comparison of transcriptomes of Anabaena sp. PCC7120 and a FurC-overexpressing derivative strain grown under standard conditions (BG11) and after 48 hours of nitrogen step-down (BG110). Anabaena sp PCC7120 is a cyanobacterium that differentiates specialized nitrogen-fixing cells ...
ORGANISM(S): Nostoc sp. PCC 7120 
2020-04-28 | E-MTAB-8996 | biostudies-arrayexpress
TranscriptomicsLentiviral vector-based microRNA sponges identifies miR-155 and miR-802 target genes in the hippocampus of Ts65Dn mice
A major challenge in Down syndrome (DS) is to understand how the extra-dose of functional chromosome 21 (HSA21) genetic elements can impact on the tissue-specific transcriptome to contribute to phenotypic alterations. MiRNAs are post-transcriptional modulators with genome-wide regulatory effects. F...
ORGANISM(S): Mus musculus 
2015-05-16 | E-GEOD-68074 | biostudies-arrayexpress
TranscriptomicsUnbalancing FurB (Zur)-mediated homeostasis in Anabaena sp. PCC7120: Consequences on heterocyst development and biofilm formation
Here, we report the comparison of transcriptomes of Anabaena sp. PCC7120 and the FurB(Zur) deletion derivative strain (MN38). Anabaena sp PCC7120 is a cyanobacterium that differentiates specialized nitrogen-fixing cells called heterocysts and that is capable of forming biofilms. Our data showed that...
ORGANISM(S): Anabaena ambigua 
2023-09-14 | E-MTAB-12347 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic stem cells carrying an extra copy of human chromosome 21 and their wild type counterparts to model Down&aposs Syndrome
Comparison of mouse embryonic stem (ES) cells carrying an extra copy of human chromosome 21 (HSA21) with their WT counterparts. The transchromosomic cells are called 47-1, and the parental WT cells are called D3.
ORGANISM(S): Mus musculus 
2008-09-04 | E-MEXP-654 | biostudies-arrayexpress
UnknownCIBERER: Spanish national network for research on rare diseases: A highly productive collaborative initiative.
Not available
S-EPMC9305285 | biostudies-literature
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