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TranscriptomicsLymphopenia-induced T cell exhaustion in STING gain-of-function mouse model
STING gain-of-function (GOF) mutations lead to T cell lymphopenia, in the context of severe combined immunodeficiency (SCID) for STING GOF V154M mice. This T cell lymphopenia, which is of central origin, has been described as type I IFN independent and associated with dysfunctions of the rare mature...
ORGANISM(S): Mus musculus 
2024-01-07 | E-MTAB-13658 | biostudies-arrayexpress
UnknownMicrocephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation.
Not available
S-EPMC3567437 | biostudies-literature
TranscriptomicsGenotyping of Arabidopsis ecotypes
Large-scale screening studies carried out to date to elucidate the causal mechanism of an allelic imbalance are generally limited to descriptions of allele-specific differences in expression detected in vivo and to linking them to differences in cis- and trans-regulatory changes. Although such gene ...
ORGANISM(S): Arabidopsis thaliana 
2006-12-02 | E-TABM-67 | biostudies-arrayexpress
Transcriptomics10X Chromium single-cell RNA sequencing of the hematopoietic system and niche cells of young and old female individuals from four distinct mouse species
The aim of this study was to analyse the evolutionary conservation or divergence of the aging murine hematopoietic system, which includes hematopoietic stem and progenitor cells (HSPCs) and stromal cells from the hematopoietic niche. The animals used were young (10-13 weeks) and old (84-109 weeks) f...
ORGANISM(S): Mus musculus castaneus 
2026-08-15 | E-MTAB-15073 | biostudies-arrayexpress
UnknownTwo Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease.
Not available
S-EPMC10794000 | biostudies-literature
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