Genotyping of Arabidopsis ecotypes

ABSTRACT: Large-scale screening studies carried out to date to elucidate the causal mechanism of an allelic imbalance are generally limited to descriptions of allele-specific differences in expression detected in vivo and to linking them to differences in cis- and trans-regulatory changes. Although such gene surveys for regulatory variation leave the underlying mechanisms unexplored, they are a first step in identifying the specific nucleotide changes that govern gene expression differences. We describe a quantitative genetics approach to distinguish between cis- and trans-regulatory changes at a genome-wide scale and, hence, to detect cis-regulatory variation. For this purpose, we took advantage of diallel designs that are often used in plant breeding programs in which the goal is the estimation of

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Fred van Eeuwijk 

PROVIDER: E-TABM-67 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress