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GenomicsMolecular role of the PAX5-ETV6 oncoprotein in promoting B cell acute lymphoblastic leukemia
PAX5 is a tumor suppressor in B-ALL, while the role of PAX5 fusion proteins in B-ALL development is largely unknown. Here we studied the function of PAX5-ETV6 and PAX5- FOXP1 in mice expressing these proteins from the Pax5 locus. Both proteins arrested Blymphopoiesis at the pro-B-to-pre-B cell trans...
ORGANISM(S): Mus musculus 
2016-07-30 | E-GEOD-84987 | biostudies-arrayexpress
Genomicsba3dbe29-0fd7-4ee5-99b8-d69d3c381e6e - samples
The BAM files for WES and RNA seq used in the article "Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases." on cancer Discovery 2019. PMID: 30787016 PMCID: PMC6497554. Authors : Grant M Fischer, ..., Michael A Davies.
EGAD00001005046 | EGA
UnknownBODIPY-Caged Photoactivated Inhibitors of Cathepsin B Flip the Light Switch on Cancer Cell Apoptosis.
Not available
S-EPMC9885843 | biostudies-literature
ProteomicsAcyldepsipeptide probes facilitate specific detection of caseinolytic protease P independent of its oligomeric and activity state
Caseinolytic protease P (ClpP) is a tetradecameric peptidase which assembles with chaperones such as ClpX to gain proteolytic activity. Acyldepsipeptides (ADEPs) represent small molecule mimics of ClpX, which bind into hydrophobic pockets on the apical site of the complex and thereby induce activati...
ORGANISM(S): Staphylococcus aureus 
2020-05-26 | PXD015244 | Pride
Thermo fischer q exactive orbitrap Photoaffinity labeling S. aureus 
UnknownRole of novel cancer gene SLITRK3 to activate NTRK3 in squamous cell lung cancer.
Not available
S-EPMC8607376 | biostudies-literature
UnknownRole of TET1 and 5hmC in an Obesity-Linked Pathway Driving Cancer Stem Cells in Triple-Negative Breast Cancer.
Not available
S-EPMC7718329 | biostudies-literature
MetabolomicsDissolved metabolites from the Bermuda Atlantic Time-series Study: 2016-2019

Organic carbon in seawater plays a significant role in the global carbon cycle. The concentration and composition of dissolved organic carbon, operationally defined in this project as organic carbon that passes through a 0.2 µm filter, reflect the actions of the biological community and chemical ...

2022-02-09 | MTBLS2356 | MetaboLights
UnknownObesity-induced MBD2_v2 expression promotes tumor-initiating triple-negative breast cancer stem cells.
Not available
S-EPMC6441886 | biostudies-literature
UnknownSchool-based gardening, cooking and nutrition intervention increased vegetable intake but did not reduce BMI: Texas sprouts - a cluster randomized controlled trial.
Not available
S-EPMC7825209 | biostudies-literature
MetabolomicsMigratory Zooplankton Excreta and its Influence on Prokaryotic Communities

Particulate organic matter (fecal pellets) from zooplankton has been demonstrated to be important nutrient sources for the pelagic prokaryotic community. Significantly less is known about the chemical composition of the dissolved organic matter (DOM) produced by these eukaryotes and its infl...

2020-11-27 | MTBLS1822 | MetaboLights
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