Sort   by:  
 Page size 
UnknownRedox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A.
Not available
S-EPMC7096751 | biostudies-literature
ProteomicsIdentification of biotinylated papaverine interactors from HEK293 total cell extract by LC-MS/MS
Aim of the project was to identify interactors of the phytochemical papaverine, modified with a biotin moiety, from HEK293 total cell extract by LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD021808 | Pride
Interactors Compound Biotinylation Papaverine Lc-ms/ms 
ProteomicsIdentification of human GRHL1 interactors and post-translational modifications by LC-MS/MS
Aim of the project was to identify interactors and post-translational modifications of recombinant 3xFLAG-6xHis-tagged human GRHL1, tandem-affinity purified from isolated HEK293 nuclei treated with DMSO as control or with the phytochemical papaverine.
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD021768 | Pride
Interactors Transcription factor Post-translational modification Grhl1 Lc-ms/ms 
TranscriptomicsGRHL1 acts as a tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3
Neuroblastoma is an embryonic solid tumor of neural crest origin and accounts for 11% of all cancer-related deaths in children. Novel therapeutic strategies are therefore urgently required. MYCN oncogene amplification, which occurs in 20% of neuroblastomas, is a hallmark of high risk. Here we aimed ...
ORGANISM(S): Homo sapiens 
2014-05-22 | E-GEOD-47407 | biostudies-arrayexpress
UnknownPopulation-based cohort imaging: skeletal muscle mass by magnetic resonance imaging in correlation to bioelectrical-impedance analysis.
Not available
S-EPMC8977960 | biostudies-literature
TranscriptomicsGenomeâ??wide transcriptional profiling with spatial resolution identifies Bone Morphogenetic Protein signaling as essential regulator of zebrafish cardiomyocyte regeneration.
In contrast to mammals, zebrafish regenerate heart injuries via proliferation of cardiomyocytes located at the wound border. Here, we show that tomo-seq can be used to identify whole-genome transcriptional profiles of the injury zone, the border zone and the healthy myocardium. Interestingly, the bo...
ORGANISM(S): Danio rerio 
2016-01-11 | E-GEOD-74652 | biostudies-arrayexpress
GenomicsSalt augments macrophage-driven host defense in the skin
Immune cells regulate a hypertonic microenvironment in the skin; however, possible functions of increased skin Na+ concentrations are unknown. We found that Na+ accumulated at the site of bacterial skin infections in humans and in mice. We used the protozoan parasite Leishmania (L.) major as a model...
ORGANISM(S): Mus musculus 
2015-02-26 | E-MTAB-3343 | biostudies-arrayexpress
UnknownMYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma.
Not available
S-EPMC5341807 | biostudies-literature
UnknownIntra-operative defibrillation testing and clinical shock efficacy in patients with implantable cardioverter-defibrillators: the NORDIC ICD randomized clinical trial.
Not available
S-EPMC4589656 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
Sort   by:  
 Page size