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TranscriptomicsTranscription profiling of Atlantic salmon following dietary substitution of fish oil with vegetable oils
There is an increasing drive to replace fish oil (FO) in finfish aquaculture diets with vegetable oils (VO), driven by the short supply of FO derived from wild fish stocks. Little is known of the consequences for fish health after such substitution. The effect of dietary VO on hepatic gene expressio...
ORGANISM(S): Salmo salar 
2008-10-27 | E-TABM-478 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of Atlantic salmon (Salmo salar) to fish oil vs vegetable oil based diets
The effect of different diets (i.e. fish oil based vs vegetable oil based) on liver transcription profiles over the life history stages (freshwater and marine phases) of cultured Atlantic salmon (Salmo salar) were explored. Two groups of fish were raised from first feeding on different lipid contai...
ORGANISM(S): Salmo salar 
2008-08-01 | E-TABM-449 | biostudies-arrayexpress
TranscriptomicsExpression data from liver of young and old rats fed on different dietary fat sources, namely virgin olive, sunflower or fish oils
Since the liver is the central organ of metabolism, changes in diet have a great impact on this organ and overall on health with aging. It is well known that dietary fat source strongly influences many parameters of the hepatic mitochondria. These changes includes modification of lipid composition o...
ORGANISM(S): Rattus norvegicus 
2014-03-26 | E-GEOD-56166 | biostudies-arrayexpress
TranscriptomicsA nutritionally-enhanced oil from transgenic Camelina sativa effectively replaces marine fish oil as a source of eicosapentaenoic acid for farmed Atlantic salmon (Salmo salar)
The use of high levels of marine fish oil in aquafeeds is a non-sustainable practice. However, more sustainable oils sources from terrestrial plants do not contain long-chain polyunsaturated fatty acids (LC-PUFA). Consequently, feeds based on conventional vegetable oils reduce n-3 LC-PUFA levels in ...
ORGANISM(S): Salmo salar 
2015-12-21 | E-MTAB-2855 | biostudies-arrayexpress
TranscriptomicsGene expression data from mouse liver
We used microarray analysis to examine which genes are differentially expressed in mice that received a combination of fish oil and indomethacin. We fed low density lipoprotein receptor knock-out (LDLR-/-) mice with 6% of olive oil (control) or fish oil diets in the presence or absence of indomethac...
ORGANISM(S): Mus sp. 
2012-11-06 | E-GEOD-23742 | biostudies-arrayexpress
TranscriptomicsGenotype-specific responses in intestinal lipid metabolism to complete dietary fish oil replacement by vegetable oil in Atlantic salmon
As part of a study investigating the effects of genotype on responses to sustainable feeds in Atlantic salmon, a microarray analysis of the intestine transcriptome of two family groups, identified as 'Lean' or 'Fat' (based on flesh lipid content), which were fed a diet containing either 100% fish oi...
ORGANISM(S): Salmo salar 
2012-03-01 | E-TABM-1173 | biostudies-arrayexpress
TranscriptomicsGenotype-specific responses in hepatic lipid metabolism to complete dietary fish oil replacement by vegetable oil in Atlantic salmon
As part of a study investigating the effects of genotype on responses to sustainable feeds in Atlantic salmon, a microarray analysis of the liver transcriptome of two family groups, identified as 'Lean' or 'Fat' (based on flesh lipid content), which were fed a diet containing either 100% fish oil (F...
ORGANISM(S): Salmo salar 
2011-01-04 | E-TABM-1089 | biostudies-arrayexpress
ClinicalThe Effect of Fish Oils on Human Hepatic Colorectal Metastases
The purpose of this study is to determine whether fish oils - a known source of omega-3 given intravenously (via a ‘drip’) will help cure secondary deposits in the liver from bowel cancer.
2075377 | ecrin-mdr-crc
ProteomicsImpact of the short chain fatty acid, sodium butyrate, on gut resident microbiota, gut mucus proteome and fish susceptibility to bacterial and parasitic infections in vivo
Previous works in the framework of EU ARRAINA Project evidenced a pro-inflammatory condition in gilthead sea bream (Sparus aurata) fed extremely low fish meal/fish oil diets, and this effect was mostly reversed by butyrate supplementation. The hypothesis of work is that these nutritionally-mediated ...
ORGANISM(S): Sparus aurata 
2018-10-24 | PXD006183 | Pride
Gut  microbiome  proteome  disease resilience Fish meal Butyrate Fish oil 
TranscriptomicsMolecular pathology of the ARF induced by choline deficiency and of the protection afforded by fish oil
Weanling rats fed a choline-deficient diet develop acute renal failure (ARF) after 6-7 days of receiving the experimental diet. Its pathogenesis is controversial. Menhaden oil has a protective effect in this experimental model. The aim of this study is to describe both the genetic profile and its ch...
ORGANISM(S): Rattus norvegicus 
2011-12-06 | E-GEOD-34139 | biostudies-arrayexpress
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